Literature DB >> 1291208

Ischemic stroke treated with Ligusticum chuanxiong.

K J Chen1, K Chen.   

Abstract

Ligusticum Chuanxiong and its effective components were studied in the treatment of ischemic stroke, a common emergent disease in China. Some injections of the medicines, including Ligusticum, Ligustrazine, Ligustylid and ferulic acid, were tested clinically and experimentally. The results showed that the effects of the drugs were the same as or even better than those of the controls, such as papaverine, dextran and aspirin-persantin. They could improve brain microcirculation through inhibiting thrombus formation and platelet aggregation as well as blood viscosity.

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Year:  1992        PMID: 1291208

Source DB:  PubMed          Journal:  Chin Med J (Engl)        ISSN: 0366-6999            Impact factor:   2.628


  17 in total

1.  Protective action of tetramethylpyrazine phosphate against dilated cardiomyopathy in cTnT(R141W) transgenic mice.

Authors:  Hai-ping Zhao; Dan Lü; Wei Zhang; Li Zhang; Shu-mei Wang; Chun-mei Ma; Chuan Qin; Lian-feng Zhang
Journal:  Acta Pharmacol Sin       Date:  2010-02-15       Impact factor: 6.150

2.  Antithrombotic effects of tetramethylpyrazine in in vivo experiments.

Authors:  J R Sheu; G Hsiao; Y M Lee; M H Yen
Journal:  Int J Hematol       Date:  2001-04       Impact factor: 2.490

3.  The prediction of plasma and brain levels of 2,3,5,6-tetramethylpyrazine following transdermal application.

Authors:  Xiaohong Qi; Chrisita Ackermann; Duxin Sun; Rong Liu; Minli Sheng; Huimin Hou
Journal:  AAPS PharmSci       Date:  2002

4.  Tetramethylpyrazine Promotes Migration of Neural Precursor Cells via Activating the Phosphatidylinositol 3-Kinase Pathway.

Authors:  Xiangying Kong; Micun Zhong; Xiaohui Su; Qingxia Qin; Hongchang Su; Hongye Wan; Cuiling Liu; Jiajia Wu; Hongcai Shang; Yanjun Zhang; Na Lin
Journal:  Mol Neurobiol       Date:  2015-11-28       Impact factor: 5.590

5.  Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension.

Authors:  Yuqin Chen; Wenju Lu; Kai Yang; Xin Duan; Mengxi Li; Xiuqing Chen; Jie Zhang; Meidan Kuang; Shiyun Liu; Xiongting Wu; Guofa Zou; Chunli Liu; Cheng Hong; Wenjun He; Jing Liao; Chi Hou; Zhe Zhang; Qiuyu Zheng; Jiyuan Chen; Nuofu Zhang; Haiyang Tang; Rebecca R Vanderpool; Ankit A Desai; Franz Rischard; Stephen M Black; Joe G N Garcia; Ayako Makino; Jason X-J Yuan; Nanshan Zhong; Jian Wang
Journal:  Br J Pharmacol       Date:  2020-04-27       Impact factor: 8.739

6.  Tetramethylpyrazine Protects Retinal Capillary Endothelial Cells (TR-iBRB2) against IL-1β-Induced Nitrative/Oxidative Stress.

Authors:  Xue Zhu; Ke Wang; Kai Zhang; Xuhua Tan; Zhifeng Wu; Song Sun; Fanfan Zhou; Ling Zhu
Journal:  Int J Mol Sci       Date:  2015-09-09       Impact factor: 5.923

Review 7.  An Analysis of the Combination Frequencies of Constituent Medicinal Herbs in Prescriptions for the Treatment of Stroke in Korean Medicine: Determination of a Group of Candidate Prescriptions for Universal Use.

Authors:  Byeong Cheol Yun; Seung Bin Pae; Yoo Kyoung Han; Moo Jin Choi; Byung Tae Choi; Hwa Kyoung Shin; Jin Ung Baek
Journal:  Evid Based Complement Alternat Med       Date:  2016-03-20       Impact factor: 2.629

8.  Neural protection by naturopathic compounds-an example of tetramethylpyrazine from retina to brain.

Authors:  Zhiqun Tan
Journal:  J Ocul Biol Dis Infor       Date:  2009-07-14

9.  Erratum: Neural protection by naturopathic compounds-an example of tetramethylpyrazine from retina to brain.

Authors:  Zhiqun Tan
Journal:  J Ocul Biol Dis Infor       Date:  2009-09-01

10.  Therapeutic Effect of External Application of Ligustrazine Combined with Holistic Nursing on Pressure Sores.

Authors:  Junzhi Niu; Lin Han; Fen Gong
Journal:  Med Sci Monit       Date:  2016-08-15
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