Literature DB >> 12911015

Protein-deficient diet in pregnant females impairs functional activity of enzyme systems in digestive and non-digestive organs in the offspring.

N M Timofeeva1, L A Gordova, V V Egorova, A A Nikitina.   

Abstract

Activity of disaccharidases in various portions of the small intestine markedly increased in 6-month-old offspring of pregnant females feeding a protein-deficient diet. Activities of amino- and dipeptidases decreased in the kidneys, while alkaline phosphatase activity remained practically unchanged. Probably, information about protein restriction in nutrition of pregnant females is stored in the biochemical memory of adult offspring and promotes the development of metabolic disturbances.

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Year:  2003        PMID: 12911015     DOI: 10.1023/a:1023847226313

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  2 in total

1.  Modulations in the intestinal disaccharide hydrolases and membrane dynamics: effect of non-steroidal anti-inflammatory drugs aspirin and nimesulide.

Authors:  Naveen Kaushal; S N Sanyal
Journal:  Mol Cell Biochem       Date:  2006-07-20       Impact factor: 3.396

2.  Maternal protein restriction affects gene expression and enzyme activity of intestinal disaccharidases in adult rat offspring.

Authors:  D F Pinheiro; P D G Pacheco; P V Alvarenga; J Buratini; A C S Castilho; P F Lima; D R S Sartori; M L M Vicentini-Paulino
Journal:  Braz J Med Biol Res       Date:  2013-03-15       Impact factor: 2.590

  2 in total

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