Literature DB >> 12904400

Evaluation of a rapid PCR assay for diagnosis of meningococcal meningitis.

David C Richardson1, Lisa Louie, Marie Louie, Andrew E Simor.   

Abstract

We compared the results of Gram staining and culture of cerebrospinal fluid to results obtained with a rapid PCR assay for the diagnosis of meningococcal meningitis in 281 cases of suspected bacterial meningitis. PCR had a sensitivity of 97% compared to a sensitivity of 55% for culture, and the PCR specificity was 99.6%. PCR results were available within 2 h of the start of the assay.

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Year:  2003        PMID： 12904400      PMCID： PMC179789          DOI： 10.1128/JCM.41.8.3851-3853.2003

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  15 in total

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Review 3.  Laboratory diagnosis of bacterial meningitis.

Authors:  L D Gray; D P Fedorko
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Authors:  C W Jarvis; K M Saxena
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Authors:  H P Dalton; M J Allison
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6.  The changing epidemiology of invasive meningococcal disease in Canada, 1985 through 1992. Emergence of a virulent clone of Neisseria meningitidis.

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Journal:  J Clin Microbiol       Date:  1996-07       Impact factor: 5.948

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Review 9.  Early management of meningococcal disease.

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Journal:  J Infect       Date:  2000-01       Impact factor: 6.072
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6.  Meningitis dipstick rapid test: evaluating diagnostic performance during an urban Neisseria meningitidis serogroup A outbreak, Burkina Faso, 2007.

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Journal:  PLoS One       Date:  2010-06-11       Impact factor: 3.240

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8.  Direct detection and serogroup characterization of Neisseria meningitidis from outbreak of meningococcal meningitis in Delhi.

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9.  Accuracy of real-time PCR, Gram stain and culture for Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae meningitis diagnosis.

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10.  A versatile PDMS/paper hybrid microfluidic platform for sensitive infectious disease diagnosis.

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