| Literature DB >> 12904006 |
Wenjun Tang1, Shulin Wu, Xumu Zhang.
Abstract
Hydrogenation of a series of cyclic beta-(acylamino)acrylates with tetrasubstituted olefins has been accomplished successfully with the use of Ru catalysts with chiral biaryl ligands such as C3-TunaPhos, and up to over 99% ee's have been achieved. This methodology provides an efficient catalytic method for the synthesis of both cis and trans chiral cyclic beta-amino acid derivatives.Entities:
Mesh：
Substances：
Year: 2003 PMID： 12904006 DOI： 10.1021/ja035777h
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419