| Literature DB >> 12903275 |
S Kumar1, K K Dubey, S Tripathi, M Fujii, K Misra.
Abstract
Di-O-glycinoyl curcumin (I), di-O-glycinoyl-C4-glycyl-curcumin (II), 5'-deoxy-5'-curcuminyl thymidine (5'-cur-T) (III) and 2'-deoxy-2'-curcuminyl uridine (2'-cur-U) (IV) have been synthesized and characeterised by elemental analysis & 1H NMR. The antibacterial activities of these four bioconjugates has been tested particularly for multiresistant micro-organisms. Best results are shown by I & IV. These bioconjugates serve dual purpose of systemic delivery as well as therapeutic agents against viral diseases.Entities:
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Year: 2000 PMID： 12903275 DOI： 10.1093/nass/44.1.75
Source DB: PubMed Journal: Nucleic Acids Symp Ser ISSN： 0261-3166