Literature DB >> 12903208

Functional regulation of biomolecule using DNA-conjugation.

Takahisa Anada1, Takeshi Kano, Wataru Kaku, Yoshiki Katayama, Mizuo Maeda, Masaharu Murata.   

Abstract

3'-methacryloyl-oligodeoxynucleotide having antisense sequence against messenger RNA of green fluorescent protein and N-isopropylacrylamide were co-polymerized. The conjugate can reversibly change its conformation at around a transition temperature, similarly to N-isopropylacrylamide homopolymer. We achieved artificially regulation of gene expression depending on temperature using the conjugate.

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Year:  2002        PMID: 12903208     DOI: 10.1093/nass/2.1.269

Source DB:  PubMed          Journal:  Nucleic Acids Res Suppl


  1 in total

Review 1.  Nucleoside, nucleotide and oligonucleotide based amphiphiles: a successful marriage of nucleic acids with lipids.

Authors:  Arnaud Gissot; Michel Camplo; Mark W Grinstaff; Philippe Barthélémy
Journal:  Org Biomol Chem       Date:  2008-03-05       Impact factor: 3.876

  1 in total

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