L Falk1, H Fredlund, J S Jensen. 1. Department of Dermatology and Venereology, Orebro University Hospital, Orebro, Sweden. lars.falk@orebroll.se
Abstract
OBJECTIVES: To study the treatment efficacy of tetracyclines and azithromycin in Mycoplasma genitalium positive patients attending an STD clinic. METHODS: All M genitalium positive patients (34 men and 26 women) attending an STD clinic during a 6 month period were treated with antibiotics. All patients known to be partners of M genitalium positive patients and those who were M genitalium positive, but not initially treated, were treated with azithromycin. Patients with urethritis and/or cervicitis were treated with tetracyclines before their M genitalium status was known. RESULTS: 10 of 14 women (71%) and 10 of 16 men (63%) treated with tetracyclines were M genitalium positive at follow up, whereas all patients treated with azithromycin (16 men and 20 women) were M genitalium negative, at the 4 week follow up visit. CONCLUSIONS: These results suggest that tetracyclines are not sufficient to eradicate M genitalium. Randomised controlled treatment trials are urgently needed.
OBJECTIVES: To study the treatment efficacy of tetracyclines and azithromycin in Mycoplasma genitalium positive patients attending an STD clinic. METHODS: All M genitalium positive patients (34 men and 26 women) attending an STD clinic during a 6 month period were treated with antibiotics. All patients known to be partners of M genitalium positive patients and those who were M genitalium positive, but not initially treated, were treated with azithromycin. Patients with urethritis and/or cervicitis were treated with tetracyclines before their M genitalium status was known. RESULTS: 10 of 14 women (71%) and 10 of 16 men (63%) treated with tetracyclines were M genitalium positive at follow up, whereas all patients treated with azithromycin (16 men and 20 women) were M genitalium negative, at the 4 week follow up visit. CONCLUSIONS: These results suggest that tetracyclines are not sufficient to eradicate M genitalium. Randomised controlled treatment trials are urgently needed.
Authors: J R Schwebke; A Rompalo; S Taylor; A C Seña; D H Martin; L M Lopez; S Lensing; J Y Lee Journal: Clin Infect Dis Date: 2011-01-15 Impact factor: 9.079
Authors: Lisa E Manhart; Catherine W Gillespie; M Sylvan Lowens; Christine M Khosropour; Danny V Colombara; Matthew R Golden; Navneet R Hakhu; Katherine K Thomas; James P Hughes; Nicole L Jensen; Patricia A Totten Journal: Clin Infect Dis Date: 2012-12-07 Impact factor: 9.079