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Literature DB >> 12901956

T helper type-2 cytokine responses: potential therapeutic targets.

Abstract

T helper (Th)2 cell-mediated immune responses are associated with parasitic helminth infections and atopic disorders. The production of interleukin (IL)-4, IL-5, IL-9 and/or IL-13 by Th2 cells mediates a range of responses that can be protective or pathogenic. Progress has recently been made in elucidating the mechanism of Th2 immunity, which has therapeutic potential for the treatment of allergic diseases.

Entities: Disease Gene

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Year: 2003 PMID： 12901956 DOI： 10.1016/s1471-4892(03)00077-8

Source DB: PubMed Journal: Curr Opin Pharmacol ISSN： 1471-4892 Impact factor: 5.547

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Cited

7 in total

1. CD8 T cells modulate CD4 T-cell and eosinophil-mediated pulmonary pathology in pneumocystis pneumonia in B-cell-deficient mice.

Authors: Steve D Swain; Nicole N Meissner; Allen G Harmsen
Journal: Am J Pathol Date: 2006-02 Impact factor: 4.307

2. Changes in immune responses to antigen applied to tape-stripped skin with CpG-oligodeoxynucleotide in NC/Nga mice.

Authors: Joe Inoue; Satoshi Yotsumoto; Takatoshi Sakamoto; Seishi Tsuchiya; Yukihiko Aramaki
Journal: Pharm Res Date: 2005-09-26 Impact factor: 4.200

3. The adjuvanticity of an O. volvulus-derived rOv-ASP-1 protein in mice using sequential vaccinations and in non-human primates.

Authors: Jing Wang; Nancy Tricoche; Lanying Du; Meredith Hunter; Bin Zhan; Gaddam Goud; Elizabeth S Didier; Jing Liu; Lu Lu; Preston A Marx; Shibo Jiang; Sara Lustigman
Journal: PLoS One Date: 2012-05-17 Impact factor: 3.240

T helper type-2 cytokine responses: potential therapeutic targets.

1. CD8 T cells modulate CD4 T-cell and eosinophil-mediated pulmonary pathology in pneumocystis pneumonia in B-cell-deficient mice.

2. Changes in immune responses to antigen applied to tape-stripped skin with CpG-oligodeoxynucleotide in NC/Nga mice.

3. The adjuvanticity of an O. volvulus-derived rOv-ASP-1 protein in mice using sequential vaccinations and in non-human primates.

Review 4. Host response mechanisms in periodontal diseases.

5. Protective effects of the polyphenol sesamin on allergen-induced T(H)2 responses and airway inflammation in mice.

6. Human CD4 memory T cells can become CD4+IL-9+ T cells.

7. Astragalus polysaccharide enhances immunity and inhibits H9N2 avian influenza virus in vitro and in vivo.