| Literature DB >> 12901926 |
Eisaku Nomura1, Ayumi Kashiwada, Asao Hosoda, Kozo Nakamura, Hideko Morishita, Takuo Tsuno, Hisaji Taniguchi.
Abstract
We prepared amide compounds which were derived from ferulic acid using various amines, and investigated their stimulatory effects on insulin secretion using rat pancreatic RIN-5F cells. Most of these compounds exhibited significant promotion of the insulin-release at a concentration of 10 microM and in particular, the amides having n-butyl, n-pentyl, pyrrolidine, and piperidine groups showed high activity.Entities:
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Year: 2003 PMID： 12901926 DOI： 10.1016/s0968-0896(03)00280-3
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641