Literature DB >> 12898243

Mechanisms of death in the early postoperative period following coronary artery bypass grafting for acquired heart disease. A clinicopathological study of 32 cases.

Tibor Glasz1, Michael Frenken, Hans-Jürgen Knieriem, Arno Krian.   

Abstract

OBJECTIVES: A retrospective cardiopathological and clinical study was conducted in order to determine causes of perioperative death following coronary artery bypass grafting (CABG). EXPERIMENTAL
DESIGN: Between January 1992 and June 1995, a total of 5749 CABG procedures were performed at the Heart Center Duisburg (Germany). Following the procedures, 218 patients died in hospital (mortality rate 3.8%). Fifty-eight were autopsied at the Institute of Pathology, Bethesda Hospital, Duisburg, and 32 autopsied cases were amenable to our study. Basis for selection was accessibility of clinical and morphological data and a postoperative death within 30 days.
METHODS: In each case, morphological analysis of the heart and an evaluation of surgical and clinical data were performed in order to draw a conclusion on the mechanism of death.
RESULTS: Using criteria defined by us, the following causes of death were determined: (1) surgical complications (43%); (2) severe coronary artery disease with incomplete revascularization (41%); (3) congestive heart failure (13%); (4) non-cardiac complications (3%).
CONCLUSION: Criteria defined in this study may be useful in evaluations of causes of death after open heart surgery and may help to compare results in future series. Determination of the cause of death is important for the cardiac surgeon to reconsider indications and quality of surgical procedure.

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Year:  2003        PMID: 12898243     DOI: 10.1007/s00428-003-0848-5

Source DB:  PubMed          Journal:  Virchows Arch        ISSN: 0945-6317            Impact factor:   4.064


  29 in total

1.  Postoperative death should be followed by autopsy - an analysis of the autopsy findings of the years 1990 and 1991 in a heart surgery center.

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Journal:  Heart Vessels       Date:  1995       Impact factor: 2.037

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Journal:  Annu Rev Med       Date:  1980       Impact factor: 13.739

7.  Biochemical and ultrastructural integrity of the saphenous vein conduit during coronary artery bypass grafting. Preliminary results of the effect of papaverine.

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Journal:  J Thorac Cardiovasc Surg       Date:  1984-07       Impact factor: 5.209

8.  Accelerated "atherosclerosis". A morphologic study of 97 saphenous vein coronary artery bypass grafts.

Authors:  B H Bulkley; G M Hutchins
Journal:  Circulation       Date:  1977-01       Impact factor: 29.690

9.  Anterior wall myocardial infarction in a 15-year-old diabetic female associated with spontaneously resolving coronary thrombosis.

Authors:  C S Kovacs; A J Sanfilippo; G W Burggraf
Journal:  Can J Cardiol       Date:  1992-09       Impact factor: 5.223

10.  Primary myocardial revascularization. Trends in surgical mortality.

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Journal:  J Thorac Cardiovasc Surg       Date:  1984-11       Impact factor: 5.209

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Authors:  Marius J Swart; Gina Joubert; Jan-Albert van den Berg; Gert J van Zyl
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