Literature DB >> 12898035

[Polymerase chain reaction in the urinary diagnosis of bladder cancer].

W-D Beecken1, D Jonas.   

Abstract

The polymerase chain reaction (PCR) is a highly sensitive and specific method for the detection of genetic material. Over the last few years, this method has been used increasingly for the molecular detection of disease. This report demonstrates the use of PCR in the diagnosis of bladder cancer. The principles of the method are shown by describing the detection of p53, CD44 and telomerase, as well as in microsatellite analysis.

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Year:  2003        PMID： 12898035     DOI： 10.1007/s00120-003-0308-5

Source DB:  PubMed          Journal:  Urologe A        ISSN： 0340-2592            Impact factor:   0.639


  16 in total

1.  Limitations of urinary telomerase activity measurement in urothelial cancer.

Authors:  Y Arai; T Yajima; A Yagihashi; D Kobayashi; H Kameshima; M Sasaki; K Tanaka; K Kuwajima; N Miyao; T Tsukamoto; N Watanabe
Journal:  Clin Chim Acta       Date:  2000-06       Impact factor: 3.786

2.  Multiple variants of the human lymphocyte homing receptor CD44 generated by insertions at a single site in the extracellular domain.

Authors:  D G Jackson; J Buckley; J I Bell
Journal:  J Biol Chem       Date:  1992-03-05       Impact factor: 5.157

3.  Microsatellite analysis of free tumor DNA in urine, serum, and plasma of patients: a minimally invasive method for the detection of bladder cancer.

Authors:  Michael Utting; Wolfram Werner; Regine Dahse; Jörg Schubert; Kerstin Junker
Journal:  Clin Cancer Res       Date:  2002-01       Impact factor: 12.531

4.  Detection of bladder cancer recurrence by microsatellite analysis of urine.

Authors:  G Steiner; M P Schoenberg; J F Linn; L Mao; D Sidransky
Journal:  Nat Med       Date:  1997-06       Impact factor: 53.440

5.  Microsatellite analysis--DNA test in urine competes with cystoscopy in follow-up of superficial bladder carcinoma: a phase II trial.

Authors:  B W van Rhijn; I Lurkin; W J Kirkels; T H van der Kwast; E C Zwarthoff
Journal:  Cancer       Date:  2001-08-15       Impact factor: 6.860

6.  Detection of telomerase activity in exfoliated cells in urine from patients with bladder cancer.

Authors:  H Kinoshita; O Ogawa; Y Kakehi; M Mishina; K Mitsumori; N Itoh; H Yamada; T Terachi; O Yoshida
Journal:  J Natl Cancer Inst       Date:  1997-05-21       Impact factor: 13.506

7.  A possible noninvasive method for the detection of bladder cancer in patients: microsatellite analysis of free DNA in urine and blood.

Authors:  M Utting; W Werner; G Müller; J Schubert; K Junker
Journal:  Ann N Y Acad Sci       Date:  2001-09       Impact factor: 5.691

8.  Comparison of human telomerase reverse transcriptase messenger RNA and telomerase activity as urine markers for diagnosis of bladder carcinoma.

Authors:  H Bialkowska-Hobrzanska; L Bowles; B Bukala; M G Joseph; R Fletcher; H Razvi
Journal:  Mol Diagn       Date:  2000-12

9.  Prospective evaluation of genetic abnormalities and telomerase expression in exfoliated urinary cells for bladder cancer detection.

Authors:  Manuel Neves; Calin Ciofu; Frédérique Larousserie; Jocelyne Fleury; Mathilde Sibony; Antoine Flahault; Florent Soubrier; Bernard Gattegno
Journal:  J Urol       Date:  2002-03       Impact factor: 7.450

10.  Urinary cytology and competitive reverse transcriptase-polymerase chain reaction analysis of a specific CD44 variant to detect and monitor bladder cancer.

Authors:  H Miyake; I Hara; K Gohji; K Yamanaka; S Arakawa; S Kamidono
Journal:  J Urol       Date:  1998-12       Impact factor: 7.450
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