Literature DB >> 12897197

Denying the wolf access to sheep's clothing.

Theo Heller1, Jay H Hoofnagle.   

Abstract

Hepatitis delta virus (HDV) is a cause of acute and chronic liver disease for which no effective therapy is currently available. Previous research has demonstrated that prenylation of the large HDV antigen is essential for viral assembly. A new report describes a novel small animal model for HDV replication and demonstrates that prenylation inhibitors are highly effective at clearing viremia and thus have potential relevance for the treatment of chronic delta hepatitis.

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Year:  2003        PMID： 12897197      PMCID： PMC166305          DOI： 10.1172/JCI19417

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  14 in total

Review 1.  Protein prenylation: genes, enzymes, targets, and functions.

Authors:  W R Schafer; J Rine
Journal:  Annu Rev Genet       Date:  1992       Impact factor: 16.830

2.  Structural requirements for RNA editing in hepatitis delta virus: evidence for a uridine-to-cytidine editing mechanism.

Authors:  J L Casey; K F Bergmann; T L Brown; J L Gerin
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-01       Impact factor: 11.205

Review 3.  A replication cycle for viroids and other small infectious RNA's.

Authors:  A D Branch; H D Robertson
Journal:  Science       Date:  1984-02-03       Impact factor: 47.728

4.  Lamivudine for chronic delta hepatitis.

Authors:  D T Lau; E Doo; Y Park; D E Kleiner; P Schmid; M C Kuhns; J H Hoofnagle
Journal:  Hepatology       Date:  1999-08       Impact factor: 17.425

Review 5.  Type B and D viral hepatitis: epidemiological changes in Southern Europe.

Authors:  G B Gaeta; G Stornaiuolo; D F Precone
Journal:  Forum (Genova)       Date:  2001 Apr-Jun

6.  Structure, sequence and expression of the hepatitis delta (delta) viral genome.

Authors:  K S Wang; Q L Choo; A J Weiner; J H Ou; R C Najarian; R M Thayer; G T Mullenbach; K J Denniston; J L Gerin; M Houghton
Journal:  Nature       Date:  1986 Oct 9-15       Impact factor: 49.962

7.  Ribonucleoprotein complexes of hepatitis delta virus.

Authors:  W S Ryu; H J Netter; M Bayer; J Taylor
Journal:  J Virol       Date:  1993-06       Impact factor: 5.103

8.  Transmission of the hepatitis B virus-associated delta antigen to chimpanzees.

Authors:  M Rizzetto; M G Canese; J L Gerin; W T London; D L Sly; R H Purcell
Journal:  J Infect Dis       Date:  1980-05       Impact factor: 5.226

9.  In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virus.

Authors:  Bruno B Bordier; Junko Ohkanda; Ping Liu; So-Young Lee; F H Salazar; Patricia L Marion; Kazuo Ohashi; Leonard Meuse; Mark A Kay; John L Casey; Said M Sebti; Andrew D Hamilton; Jeffrey S Glenn
Journal:  J Clin Invest       Date:  2003-08       Impact factor: 14.808

10.  Chronic hepatitis in carriers of hepatitis B surface antigen, with intrahepatic expression of the delta antigen. An active and progressive disease unresponsive to immunosuppressive treatment.

Authors:  M Rizzetto; G Verme; S Recchia; F Bonino; P Farci; S Aricò; R Calzia; A Picciotto; M Colombo; H Popper
Journal:  Ann Intern Med       Date:  1983-04       Impact factor: 25.391
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  1 in total

Review 1.  Hepatitis delta: epidemiology, diagnosis and management 36 years after discovery.

Authors:  Mazen Noureddin; Robert Gish
Journal:  Curr Gastroenterol Rep       Date:  2014-01
  1 in total

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