Literature DB >> 12894977

Effect of spurt duration on the heat transfer dynamics during cryogen spray cooling.

Guillermo Aguilar1, Guo-Xiang Wang, J Stuart Nelson.   

Abstract

Although cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during laser dermatologic surgery, optimization of the current cooling approach is needed to permit the safe use of higher light doses, which should improve the therapeutic outcome in many patients. The objective of this study was to measure the effect of spurt duration (delta t) on the heat transfer dynamics during CSC using a model skin phantom. A fast-response temperature sensor was constructed to record the changes in surface temperature during CSC. Temperature measurements as a function of delta t at two nozzle-to-skin distances (z = 50 and 20 mm) were performed. The average surface heat fluxes (q) and heat transfer coefficients (h) for each delta t were computed using an inverse heat conduction problem algorithm. It was observed that q undergoes a marked dynamic variation during the entire delta t, with a maximum heat flux (qc) occurring early in the spurt (5-15 ms), followed by a quick decrease. The estimated qc vary from 450 to 600 kW m(-2), corresponding to h maxima of 10 and 17-22 kW m(-2) K(-1) for z = 50 and 20 mm, respectively. For z = 50 mm, spurts longer than 40 ms do not increase the total heat removal (Q) within the first 200 ms. However, for z = 20 mm, delta t longer than 100 ms are required to achieve the same Q. It is shown that the heat transfer dynamics and the time it takes to reach qc during CSC can be understood through classic boiling theory as a transition from transient to nucleate boiling. Based on the results of this model skin phantom, it is shown that spurts longer than 40 ms have a negligible impact on both q and Q within clinically relevant cooling times (10-100 ms).

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Year:  2003        PMID: 12894977     DOI: 10.1088/0031-9155/48/14/309

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  3 in total

1.  Fluid and thermal dynamics of cryogen sprays impinging on a human tissue phantom.

Authors:  Walfre Franco; Henry Vu; Wangcun Jia; J Stuart Nelson; Guillermo Aguilar
Journal:  J Biomech Eng       Date:  2008-10       Impact factor: 2.097

2.  Numerical optimization of sequential cryogen spray cooling and laser irradiation for improved therapy of port wine stain.

Authors:  Matija Milanič; Wangcun Jia; J Stuart Nelson; Boris Majaron
Journal:  Lasers Surg Med       Date:  2011-02       Impact factor: 4.025

3.  Efficacy evaluation and treatment parameter optimization for laser surgery of Ota's nevus based on an advanced non-equilibrium bio-tissue heat transfer model.

Authors:  Jiameng Tian; Bin Chen; Dong Li
Journal:  Lasers Med Sci       Date:  2021-02-08       Impact factor: 3.161

  3 in total

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