Literature DB >> 12894855

Autologous recovery with protractedly undetectable donor chimerisms can precede stable donor engraftment in a nonmyeloablative cord blood transplant.

William Hwang Ying Khee1, Patrick Tan Huat Chye, Tan Cheng Hoe, How Gee Fung, Heng Khee Khiang, Goh Yeow Tee.   

Abstract

Low levels of donor chimerism on day 28 after hematopoietic stem cell transplantation are highly predictive of a subsequent rejection of donor cells A recent report on nonmyeloablative transplants has demonstrated that patients who engrafted after transplantation had at least 10% donor cells detectable at this time point. A patient is described who received a nonmyeloablative umbilical cord blood transplant and experienced subsequent full engraftment of donor cells despite the absence of donor chimerism at 4 weeks posttransplantation.

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Year:  2003        PMID： 12894855     DOI： 10.1007/bf02983244

Source DB:  PubMed          Journal:  Int J Hematol        ISSN： 0925-5710            Impact factor:   2.490


  8 in total

1.  Comparison of marrow and blood cell yields from the same donors in a double-blind, randomized study of allogeneic marrow vs blood stem cell transplantation.

Authors:  S Singhal; R Powles; S Kulkarni; J Treleaven; B Sirohi; B Millar; V Shepherd; R Saso; A Rowland; S Long; S Cabral; C Horton; J Mehta
Journal:  Bone Marrow Transplant       Date:  2000-03       Impact factor: 5.483

2.  Hematopoietic stem-cell transplants using umbilical-cord blood.

Authors:  E Gluckman
Journal:  N Engl J Med       Date:  2001-06-14       Impact factor: 91.245

3.  Successful allogeneic engraftment of mismatched unrelated cord blood following a nonmyeloablative preparative regimen.

Authors:  D A Rizzieri; G D Long; J J Vredenburgh; C Gasparetto; A Morris; T T Stenzel; P Davis; N J Chao
Journal:  Blood       Date:  2001-12-01       Impact factor: 22.113

4.  Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors.

Authors:  M J Laughlin; J Barker; B Bambach; O N Koc; D A Rizzieri; J E Wagner; S L Gerson; H M Lazarus; M Cairo; C E Stevens; P Rubinstein; J Kurtzberg
Journal:  N Engl J Med       Date:  2001-06-14       Impact factor: 91.245

5.  Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay.

Authors:  J C Wang; M Doedens; J E Dick
Journal:  Blood       Date:  1997-06-01       Impact factor: 22.113

6.  Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects.

Authors:  P A McSweeney; D Niederwieser; J A Shizuru; B M Sandmaier; A J Molina; D G Maloney; T R Chauncey; T A Gooley; U Hegenbart; R A Nash; J Radich; J L Wagner; S Minor; F R Appelbaum; W I Bensinger; E Bryant; M E Flowers; G E Georges; F C Grumet; H P Kiem; B Torok-Storb; C Yu; K G Blume; R F Storb
Journal:  Blood       Date:  2001-06-01       Impact factor: 22.113

7.  Graft-versus-host disease in children who have received a cord-blood or bone marrow transplant from an HLA-identical sibling. Eurocord and International Bone Marrow Transplant Registry Working Committee on Alternative Donor and Stem Cell Sources.

Authors:  V Rocha; J E Wagner; K A Sobocinski; J P Klein; M J Zhang; M M Horowitz; E Gluckman
Journal:  N Engl J Med       Date:  2000-06-22       Impact factor: 91.245

8.  Comparison of the coexpression of CD38, CD33 and HLA-DR antigens on CD34+ purified cells from human cord blood and bone marrow.

Authors:  C De Bruyn; A Delforge; D Bron; M Bernier; M Massy; P Ley; D de Hemptinne; P Stryckmans
Journal:  Stem Cells       Date:  1995-05       Impact factor: 6.277
  8 in total

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