Literature DB >> 12892014

[Mycobacterium haemophilum as the cause of lymphadenitis in the neck in an otherwise healthy boy].

E J van de Griendt1, P J Rietra, R N van Andel.   

Abstract

In an 8.5-year-old boy with severe recurring unilateral swelling of the neck, infection with Mycobacterium haemophilum was established. In addition to the more usual causative agents, cervical lymphadenopathy in children can, in rare cases, be caused by M. haemophilum. The skin tests did not differentiate between Mycobacterium avium and Mycobacterium tuberculosis infection. There was no evidence of specific immune deficiencies. The swelling did not respond to treatment with four tuberculostatic drugs (rifampicin, isoniazid, pyrazinamide and ethambutole), nor to repeated surgical excision. Finally, M. haemophilum grew on the culture despite sub-optimal culture conditions. Thereupon the patient was treated with co-trimoxazole and recovered in two weeks. This is the first patient with cervical lymphadenopathy caused by M. haemophilum to be described in the Netherlands. M. haemophilum grows on an iron-rich medium at a relatively low temperature (30-32 degrees C). In cases of cervical lymphadenopathy, it is advisable to consider M. haemophilum as a cause and to adjust the culture conditions accordingly.

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Year:  2003        PMID: 12892014

Source DB:  PubMed          Journal:  Ned Tijdschr Geneeskd        ISSN: 0028-2162


  4 in total

1.  Mycobacterium haemophilum as a novel etiology of cervical lymphadenitis in an otherwise healthy adult patient.

Authors:  Theobald J C Minani; Michael A Saubolle; Edwin Yu; Zdenek Sussland
Journal:  J Clin Microbiol       Date:  2010-05-19       Impact factor: 5.948

Review 2.  Clinical manifestations, diagnosis, and treatment of Mycobacterium haemophilum infections.

Authors:  Jerome A Lindeboom; Lesla E S Bruijnesteijn van Coppenraet; Dick van Soolingen; Jan M Prins; Eduard J Kuijper
Journal:  Clin Microbiol Rev       Date:  2011-10       Impact factor: 26.132

3.  Real-time PCR assay using fine-needle aspirates and tissue biopsy specimens for rapid diagnosis of mycobacterial lymphadenitis in children.

Authors:  E S Bruijnesteijn Van Coppenraet; J A Lindeboom; J M Prins; M F Peeters; E C J Claas; E J Kuijper
Journal:  J Clin Microbiol       Date:  2004-06       Impact factor: 5.948

4.  Mycobacterium haemophilum and lymphadenitis in children.

Authors:  Lesla E S Bruijnesteijn van Coppenraet; Edward J Kuijper; Jerome A Lindeboom; Jan M Prins; Eric C J Claas
Journal:  Emerg Infect Dis       Date:  2005-01       Impact factor: 6.883

  4 in total

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