OBJECTIVES: To investigate the changes of liver function during the course of serious acute respiratory syndrome (SARS) and to explore its possible influence factors. METHODS: There were 91 patients with common SARS, and 23 patients with severe SARS, and 61 common pneumonia patients served as the controls. The liver functions of all the patients were measured. RESULTS: The rate of anomaly liver function in the common SARS patients group was 68.1%, which was higher than that in the common pneumonia patients group (24.6%), chi2=27.7, P<0.01. The changes mainly existed in the mild to moderate elevation of alanine aminotransferase and aspartate aminotransferase. The severe SARS patients were older and the changing rate of liver function was as high as 95.7%. CONCLUSIONS: The damage possibility of liver function in SARS patients is higher than that in common pneumonia patients. The damage is light and related to SARS itself. The damage of liver function in the severe SARS patients may have close relationship with age.
OBJECTIVES: To investigate the changes of liver function during the course of serious acute respiratory syndrome (SARS) and to explore its possible influence factors. METHODS: There were 91 patients with common SARS, and 23 patients with severe SARS, and 61 common pneumoniapatients served as the controls. The liver functions of all the patients were measured. RESULTS: The rate of anomaly liver function in the common SARSpatients group was 68.1%, which was higher than that in the common pneumoniapatients group (24.6%), chi2=27.7, P<0.01. The changes mainly existed in the mild to moderate elevation of alanine aminotransferase and aspartate aminotransferase. The severe SARSpatients were older and the changing rate of liver function was as high as 95.7%. CONCLUSIONS: The damage possibility of liver function in SARSpatients is higher than that in common pneumoniapatients. The damage is light and related to SARS itself. The damage of liver function in the severe SARSpatients may have close relationship with age.
Authors: Andrea Marzi; Thomas Gramberg; Graham Simmons; Peggy Möller; Andrew J Rennekamp; Mandy Krumbiegel; Martina Geier; Jutta Eisemann; Nadine Turza; Bertrand Saunier; Alexander Steinkasserer; Stephan Becker; Paul Bates; Heike Hofmann; Stefan Pöhlmann Journal: J Virol Date: 2004-11 Impact factor: 5.103
Authors: Heike Hofmann; Kim Hattermann; Andrea Marzi; Thomas Gramberg; Martina Geier; Mandy Krumbiegel; Seraphin Kuate; Klaus Uberla; Matthias Niedrig; Stefan Pöhlmann Journal: J Virol Date: 2004-06 Impact factor: 5.103
Authors: Michał Kukla; Karolina Skonieczna-Żydecka; Katarzyna Kotfis; Dominika Maciejewska; Igor Łoniewski; Luis F Lara; Monika Pazgan-Simon; Ewa Stachowska; Mariusz Kaczmarczyk; Anastasios Koulaouzidis; Wojciech Marlicz Journal: J Clin Med Date: 2020-05-11 Impact factor: 4.241