BACKGROUND: Nosocomial infections are an important public health problem in many developing countries, particularly in the intensive care unit (ICU). Limited data exists on the incidence and burden of nosocomial infection in the ICU in Argentina. METHODS: We performed baseline prospective nosocomial infection surveillance of all patients for 6 months in 3 medical-surgical ICUs (MS-ICUs) in Argentina (2 months in each ICU). Nosocomial infections were identified using the Centers for Disease Control and Prevention National Nosocomial Infections Surveillance definitions. Overall and site-specific nosocomial infection rates, attributable mortality, and excess length of hospital stay were calculated. RESULTS: The overall nosocomial infection rate was 27% and 90 per 1000 patient-days. The most common site of infection was catheter-related bloodstream infection (32%), followed by ventilator-associated pneumonia (25%), and catheter-associated urinary tract infection (23%). The rate of central catheter-associated bloodstream infection in the MS-ICU was 44.61 per 1000 device-days, with an attributable mortality of 25%, and 12 attributable extra days of hospital stay. The urinary catheter-associated urinary tract infection rate in the MS-ICU was 22.55 per 1000 urinary catheter-days, with an attributable mortality of 5%, and 5 excess extra days of hospital stay. The ventilator-associated pneumonia rate in the MS-ICU was 50.87 per 1000 ventilator-days with an attributable mortality of 35%, and 10 attributable extra days of hospitalization. CONCLUSION: Our study finds high rates of nosocomial infections in ICUs in Argentina, associated with a considerable attributable mortality and excess length of stay. Ongoing targeted surveillance and implementation of infection control strategies is necessary to control this growing problem.
BACKGROUND:Nosocomial infections are an important public health problem in many developing countries, particularly in the intensive care unit (ICU). Limited data exists on the incidence and burden of nosocomial infection in the ICU in Argentina. METHODS: We performed baseline prospective nosocomial infection surveillance of all patients for 6 months in 3 medical-surgical ICUs (MS-ICUs) in Argentina (2 months in each ICU). Nosocomial infections were identified using the Centers for Disease Control and Prevention National Nosocomial Infections Surveillance definitions. Overall and site-specific nosocomial infection rates, attributable mortality, and excess length of hospital stay were calculated. RESULTS: The overall nosocomial infection rate was 27% and 90 per 1000 patient-days. The most common site of infection was catheter-related bloodstream infection (32%), followed by ventilator-associated pneumonia (25%), and catheter-associated urinary tract infection (23%). The rate of central catheter-associated bloodstream infection in the MS-ICU was 44.61 per 1000 device-days, with an attributable mortality of 25%, and 12 attributable extra days of hospital stay. The urinary catheter-associated urinary tract infection rate in the MS-ICU was 22.55 per 1000 urinary catheter-days, with an attributable mortality of 5%, and 5 excess extra days of hospital stay. The ventilator-associated pneumonia rate in the MS-ICU was 50.87 per 1000 ventilator-days with an attributable mortality of 35%, and 10 attributable extra days of hospitalization. CONCLUSION: Our study finds high rates of nosocomial infections in ICUs in Argentina, associated with a considerable attributable mortality and excess length of stay. Ongoing targeted surveillance and implementation of infection control strategies is necessary to control this growing problem.
Authors: V D Rosenthal; P Lynch; W R Jarvis; I A Khader; R Richtmann; N B Jaballah; C Aygun; W Villamil-Gómez; L Dueñas; T Atencio-Espinoza; J A Navoa-Ng; M Pawar; M Sobreyra-Oropeza; A Barkat; N Mejía; C Yuet-Meng; A Apisarnthanarak Journal: Infection Date: 2011-07-06 Impact factor: 3.553
Authors: H Leblebicioglu; A N Yalcin; V D Rosenthal; I Koksal; F Sirmatel; S Unal; H Turgut; D Ozdemir; G Ersoz; C Uzun; S Ulusoy; S Esen; F Ulger; A Dilek; H Yilmaz; O Turhan; N Gunay; E Gumus; O Dursun; G Yýlmaz; S Kaya; H Ulusoy; M Cengiz; L Yilmaz; G Yildirim; A Topeli; S Sacar; H Sungurtekin; D Uğurcan; M F Geyik; A Şahin; S Erdogan; A Kaya; N Kuyucu; B Arda; F Bacakoglu Journal: Infection Date: 2013-01-26 Impact factor: 3.553
Authors: Hail M Al-Abdely; Areej Dhafer Alshehri; Victor Daniel Rosenthal; Yassir Khidir Mohammed; Weam Banjar; Pablo Wenceslao Orellano; Abdullah Mufareh Assiri; Nahla Moustafa Abedel Kader; Hessa Abdullah Al Enizy; Diaa Abdullah Mohammed; Duaa Khalil Al-Awadi; Analen Fabros Cabato; Maria Wasbourne; Randa Saliya; Rosita Gasmin Aromin; Evangelina Balon Ubalde; Hanan Hanafy Diab; Modhi Abdullah Alkamaly; Nawal Mohammed Alanazi; Ibtesam Yahia Hassan Assiry; Apsia Musa Molano; Celia Flores Baldonado; Mohamed Al-Azhary; Sharifa Al Atawi; Apsia Musa Molano; Fatima Mohammad Al Adwani; Arlu Marie Casuyon Pahilanga; Raslan Nakhla; Fatma Mohammad Al Adwani; Deepa Sasithran Nair; Grace Sindayen; Annalyn Amor Malificio; Najla Jameel Helali; Haya Barjas Al Dossari; Ashraf Kelany; Abdulmajid Ghowaizi Algethami; Leigh Yanne; Avigail Tan; Sheema Babu; Shatha Mohammad Abduljabbar; Syed Zahid Bukhari; Roaa Hasan Basri; Jeyashri Jaji Mushtaq; Hala Rushdi; Abdullah Abdulaziz Turkistani; Jerlie Mae Gonzales Celiz; Mohammed Abdullah Al Raey; Ibrahim Am Al-Zaydani Asiri; Saeed Ali Aldarani; Elizabeth Laungayan Cortez; Nadia Lynette Demaisip; Misbah Rehman Aziz; Ali Omer Abdul Aziz; Batool Al Manea; Eslam Samy; Mervat Al-Dalaton; Mohammed Jkedeb Alaliany Journal: J Infect Prev Date: 2016-10-22
Authors: Elena Volakli; Claudia Spies; Argyris Michalopoulos; A B Johan Groeneveld; Yasser Sakr; Jean-Louis Vincent Journal: Crit Care Date: 2010-03-15 Impact factor: 9.097
Authors: Manuel S Rangel-Frausto; Francisco Higuera-Ramirez; Jose Martinez-Soto; Victor D Rosenthal Journal: Ann Clin Microbiol Antimicrob Date: 2010-02-02 Impact factor: 3.944