Literature DB >> 12888263

New perspectives in arsenic-induced cell signal transduction.

Yong Qian1, Vince Castranova, Xianglin Shi.   

Abstract

Although the carcinogenicity of arsenic has been well established, the underlying molecular mechanisms have not yet been fully identified. Accumulating evidence indicates that the alteration of cellular signal transduction is directly related to the carcinogenesis of arsenic. This review focuses on recent advances in arsenic-induced signal transduction, including reactive oxygen species (ROS) production, tyrosine phosphorylation, MAPK signaling, NF-kappaB activation, cell cycle arrest, and apoptosis.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12888263     DOI： 10.1016/s0162-0134(03)00235-6

Source DB:  PubMed          Journal:  J Inorg Biochem        ISSN： 0162-0134            Impact factor:   4.155


  26 in total

Review 1.  Influence of arsenate and arsenite on signal transduction pathways: an update.

Authors:  Ingrid L Druwe; Richard R Vaillancourt
Journal:  Arch Toxicol       Date:  2010-05-26       Impact factor: 5.153

2.  Environmentally relevant concentrations of arsenite and monomethylarsonous acid inhibit IL-7/STAT5 cytokine signaling pathways in mouse CD3+CD4-CD8- double negative thymus cells.

Authors:  Huan Xu; Fredine T Lauer; Ke Jian Liu; Laurie G Hudson; Scott W Burchiel
Journal:  Toxicol Lett       Date:  2016-02-24       Impact factor: 4.372

3.  Arsenite induces a cell stress-response gene, RTP801, through reactive oxygen species and transcription factors Elk-1 and CCAAT/enhancer-binding protein.

Authors:  Lin Lin; Teresa M Stringfield; Xianglin Shi; Yan Chen
Journal:  Biochem J       Date:  2005-11-15       Impact factor: 3.857

4.  Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells.

Authors:  Tatyana A Zykova; Feng Zhu; Chengrong Lu; LeeAnn Higgins; Yasuaki Tatsumi; Yasuhito Abe; Ann M Bode; Zigang Dong
Journal:  Clin Cancer Res       Date:  2006-12-01       Impact factor: 12.531

5.  The ETS family transcription factor ELK-1 regulates induction of the cell cycle-regulatory gene p21(Waf1/Cip1) and the BAX gene in sodium arsenite-exposed human keratinocyte HaCaT cells.

Authors:  Soon Young Shin; Chang Gun Kim; Yoongho Lim; Young Han Lee
Journal:  J Biol Chem       Date:  2011-06-03       Impact factor: 5.157

6.  Perfluorooctane sulfonate (PFOS) induces reactive oxygen species (ROS) production in human microvascular endothelial cells: role in endothelial permeability.

Authors:  Yong Qian; Alan Ducatman; Rebecca Ward; Steve Leonard; Valerie Bukowski; Nancy Lan Guo; Xianglin Shi; Val Vallyathan; Vincent Castranova
Journal:  J Toxicol Environ Health A       Date:  2010

7.  Arsenic inhibits mast cell degranulation via suppression of early tyrosine phosphorylation events.

Authors:  Juyoung Shim; Rachel H Kennedy; Lisa M Weatherly; Lee M Hutchinson; Jonathan H Pelletier; Hina N Hashmi; Kayla Blais; Alejandro Velez; Julie A Gosse
Journal:  J Appl Toxicol       Date:  2016-03-28       Impact factor: 3.446

8.  JNK and STAT3 signaling pathways converge on Akt-mediated phosphorylation of EZH2 in bronchial epithelial cells induced by arsenic.

Authors:  Bailing Chen; Jia Liu; Qingshan Chang; Kevin Beezhold; Yongju Lu; Fei Chen
Journal:  Cell Cycle       Date:  2012-12-19       Impact factor: 4.534

9.  Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways.

Authors:  Xiaozhong Yu; Joshua F Robinson; Elizabeth Gribble; Sung Woo Hong; Jaspreet S Sidhu; Elaine M Faustman
Journal:  Toxicol Appl Pharmacol       Date:  2008-09-27       Impact factor: 4.219

10.  Cadmium and arsenic override NF-κB developmental regulation of the intestinal UGT1A1 gene and control of hyperbilirubinemia.

Authors:  Miao Liu; Shujuan Chen; Mei-Fei Yueh; Ryoichi Fujiwara; Camille Konopnicki; Haiping Hao; Robert H Tukey
Journal:  Biochem Pharmacol       Date:  2016-04-06       Impact factor: 5.858
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.