Literature DB >> 12888064

Autoimmune optic neuropathy with anticardiolipin antibody mimicking multiple sclerosis in a child.

Larry Frohman1, Roger Turbin, Leonard Bielory, Leo Wolansky, W Clark Lambert, Stuart Cook.   

Abstract

PURPOSE: To demonstrate that autoimmune optic neuropathy (AON) may occur in the pediatric population.
DESIGN: Interventional case report.
METHODS: A 4-year-old developed four episodes of bilateral optic neuritis with mild concurrent weakness, ataxia, or dizziness; one episode of unilateral optic neuritis; and one episode of weakness over a period of 4 years.
RESULTS: Autoimmune optic neuropathy was diagnosed because of the presence of anticardiolipin antibody and an abnormal skin biopsy with thrombin and immunoreactant deposition. She was treated with corticosteroids, aspirin, and gammaglobulin. This diminished the frequency and intensity of her attacks.
CONCLUSION: This case represents the diagnosis and treatment of AON in a child.

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Year:  2003        PMID: 12888064     DOI: 10.1016/s0002-9394(03)00156-9

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


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  4 in total

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