| Literature DB >> 1288690 |
Abstract
After chronic administration of propranolol (1 and 5 mg/kg, 14 days) to rats time-course of forced swimming changed with the decrease of rhythmical index of depression. The drug attenuated depressogenic properties of reserpine and clonidine. Propranolol antidepressive activity is attributed to blockade cerebral adrenoreceptors.Entities:
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Year: 1992 PMID: 1288690
Source DB: PubMed Journal: Biull Eksp Biol Med ISSN: 0365-9615