| Literature DB >> 12885927 |
Rosa M Dalton1, Esperanza P Pastrana, Alicia Sánchez-Fauquier.
Abstract
Human astrovirus is an important cause of acute gastroenteritis. We have generated, for the first time, a vaccinia virus recombinant expressing the astrovirus 87-kDa structural polyprotein. The results demonstrate that this expression results in the formation of virus-like particles in the absence of other astrovirus proteins and genomic RNA. The purified trypsin-activated virus-like particles strongly resemble the complete astrovirus particles.Entities:
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Year: 2003 PMID: 12885927 PMCID: PMC167206 DOI: 10.1128/jvi.77.16.9094-9098.2003
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103