BACKGROUND: Extracardiac rhabdomyomas are rare benign tumors of the head and neck. They are frequently misdiagnosed and possibly overtreated when confused with other aggressive tumors. METHODS: This article reports on the clinicopathologic features of two such tumors affecting adult patients and initially seen as slowly-growing, indolent neoplasms. RESULTS: The tumors were of fibrous consistency, mobile, with well-demarcated borders and evident lines of cleavage. Both patients were treated by conservative surgery and remained disease-free after prolonged clinical observation. Histologically, both tumors were composed of large eosinophilic cells intermingled with polyhedral clear cells. Both cell types contained abundant glycogen accumulations. CONCLUSIONS: The differential diagnosis is with granular cell tumor and with sarcomas, the former being easily distinguishable morphologically, and the latter be seen with more rapid growth and adherence to the adjacent tissues. On the basis of the preceding features, rhabdomyomas can be suspected at a preoperative stage and adequately managed with enucleation or simple excision. Copyright 2003 Wiley Periodicals, Inc.
BACKGROUND: Extracardiac rhabdomyomas are rare benign tumors of the head and neck. They are frequently misdiagnosed and possibly overtreated when confused with other aggressive tumors. METHODS: This article reports on the clinicopathologic features of two such tumors affecting adult patients and initially seen as slowly-growing, indolent neoplasms. RESULTS: The tumors were of fibrous consistency, mobile, with well-demarcated borders and evident lines of cleavage. Both patients were treated by conservative surgery and remained disease-free after prolonged clinical observation. Histologically, both tumors were composed of large eosinophilic cells intermingled with polyhedral clear cells. Both cell types contained abundant glycogen accumulations. CONCLUSIONS: The differential diagnosis is with granular cell tumor and with sarcomas, the former being easily distinguishable morphologically, and the latter be seen with more rapid growth and adherence to the adjacent tissues. On the basis of the preceding features, rhabdomyomas can be suspected at a preoperative stage and adequately managed with enucleation or simple excision. Copyright 2003 Wiley Periodicals, Inc.
Authors: Augusto César Leal da Silva Leonel; Stefanny Torres Dos Santos; Elaine Judite de Amorim Carvalho; Jurema Freire Lisboa de Castro; Oslei Paes de Almeida; Danyel Elias da Cruz Perez Journal: Head Neck Pathol Date: 2021-08-10
Authors: Ana Amelia Souza; Vera Cavalcanti de Araújo; Fabricio Passador Santos; Elizabeth Ferreira Martinez; Jose Ferreira de Menezes Filho; Ney Soares de Araujo; Andresa Borges Soares Journal: Case Rep Dent Date: 2013-10-30