Literature DB >> 1288270

Toxicological findings in a death involving dextromethorphan and terfenadine.

P Kintz1, P Mangin.   

Abstract

A case of fatal self-poisoning with dextromethorphan, an antitussive, and terfanadine, an antihistamine H1, is reported. Both drugs were quantified in several postmortem tissues and fluids using capillary gas chromatography coupled to mass spectrometry. Results are discussed in the light of the existing literature.

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Year:  1992        PMID： 1288270     DOI： 10.1097/00000433-199212000-00018

Source DB:  PubMed          Journal:  Am J Forensic Med Pathol        ISSN： 0195-7910            Impact factor:   0.921


  3 in total

1.  Mechanism of block of a human cardiac potassium channel by terfenadine racemate and enantiomers.

Authors:  T Yang; C Prakash; D M Roden; D J Snyders
Journal:  Br J Pharmacol       Date:  1995-05       Impact factor: 8.739

2.  Dextromethorphan withdrawal and dependence syndrome.

Authors:  Jochen Mutschler; Anne Koopmann; Martin Grosshans; Derik Hermann; Karl Mann; Falk Kiefer
Journal:  Dtsch Arztebl Int       Date:  2010-07-30       Impact factor: 5.594

Review 3.  Evaluating the safety and efficacy of dextromethorphan/quinidine in the treatment of pseudobulbar affect.

Authors:  Kerri A Schoedel; Sarah A Morrow; Edward M Sellers
Journal:  Neuropsychiatr Dis Treat       Date:  2014-06-26       Impact factor: 2.570
  3 in total

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