| Literature DB >> 12882482 |
Holly Van Remmen1, Michelle L Hamilton, A Richardson.
Abstract
Oxidative damage to DNA increases with age in several tissues and animal models, and mitochondrial DNA has a higher level of oxidative damage than nuclear DNA. Dietary restriction extends lifespan and is associated with reduced levels of damage to mitochondrial and nuclear DNA. The effect of exercise on DNA damage appears to be related to the intensity of the exercise.Mesh:
Substances:
Year: 2003 PMID: 12882482 DOI: 10.1097/00003677-200307000-00009
Source DB: PubMed Journal: Exerc Sport Sci Rev ISSN: 0091-6331 Impact factor: 6.230