Literature DB >> 12882348

Pre-mRNA splicing modulations in senescence.

Eran Meshorer1, Hermona Soreq.   

Abstract

Aging and associated diseases involve multilevel changes in the complex phenomenon of alternative splicing. Here, we review the potential genomic and environmental origins of such changes and discuss the research implications of these findings.

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Substances：

Year:  2002        PMID： 12882348     DOI： 10.1046/j.1474-9728.2002.00005.x

Source DB:  PubMed          Journal:  Aging Cell        ISSN： 1474-9718            Impact factor:   9.304


  28 in total

Review 1.  Cellular stress reactions as putative cholinergic links in Alzheimer's disease.

Authors:  Debra Toiber; Hermona Soreq
Journal:  Neurochem Res       Date:  2005 Jun-Jul       Impact factor: 3.996

2.  Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing.

Authors:  Lorna W Harries; Dena Hernandez; William Henley; Andrew R Wood; Alice C Holly; Rachel M Bradley-Smith; Hanieh Yaghootkar; Ambarish Dutta; Anna Murray; Timothy M Frayling; Jack M Guralnik; Stefania Bandinelli; Andrew Singleton; Luigi Ferrucci; David Melzer
Journal:  Aging Cell       Date:  2011-07-19       Impact factor: 9.304

3.  Changes in splicing factor expression are associated with advancing age in man.

Authors:  Alice C Holly; David Melzer; Luke C Pilling; Alexander C Fellows; Toshiko Tanaka; Luigi Ferrucci; Lorna W Harries
Journal:  Mech Ageing Dev       Date:  2013-06-06       Impact factor: 5.432

4.  A survey of splice variants of the human hypoxanthine phosphoribosyl transferase and DNA polymerase beta genes: products of alternative or aberrant splicing?

Authors:  Adonis Skandalis; Elke Uribe
Journal:  Nucleic Acids Res       Date:  2004-12-15       Impact factor: 16.971

5.  Pre-mRNA processing is partially impaired in satellite cell nuclei from aged muscles.

Authors:  Manuela Malatesta; Federica Perdoni; Sylviane Muller; Carlo Pellicciari; Carlo Zancanaro
Journal:  J Biomed Biotechnol       Date:  2010-05-19

6.  Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing.

Authors:  Hanna Dellago; Marlies Löscher; Paul Ajuh; Ursula Ryder; Christian Kaisermayer; Regina Grillari-Voglauer; Klaus Fortschegger; Stefan Gross; Anna Gstraunthaler; Nicole Borth; Frank Eisenhaber; Angus I Lamond; Johannes Grillari
Journal:  Biochem J       Date:  2011-08-15       Impact factor: 3.857

7.  Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target.

Authors:  G Shaltiel; M Hanan; Y Wolf; S Barbash; E Kovalev; S Shoham; H Soreq
Journal:  Brain Struct Funct       Date:  2012-01-14       Impact factor: 3.270

Review 8.  Splicing alterations in healthy aging and disease.

Authors:  Brittany Lynn Angarola; Olga Anczuków
Journal:  Wiley Interdiscip Rev RNA       Date:  2021-02-09       Impact factor: 9.957

9.  The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway.

Authors:  Uma Karthika Rajarajacholan; Subhash Thalappilly; Karl Riabowol
Journal:  PLoS Biol       Date:  2013-03-05       Impact factor: 8.029

10.  Effects of ageing on the fine distribution of the circadian CLOCK protein in reticular formation neurons.

Authors:  Manuela Malatesta; Patrizia Fattoretti; Beatrice Baldelli; Serafina Battistelli; Marta Balietti; Carlo Bertoni-Freddari
Journal:  Histochem Cell Biol       Date:  2007-04-06       Impact factor: 2.531
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