Literature DB >> 12881645

Sequence analysis of a neuropathogenic variant of Moloney murine leukemia virus ts1: evidence for recombination.

Paul Francis Szurek, James Michael Vann, Benjamin Rix Brooks.   

Abstract

The nucleotide sequence of the complete genome of ts1, a neuropathogenic variant of Moloney murine leukemia virus, has been determined. Although it is possible that the genome of ts1 accumulated point mutations during reverse transcription, our results now indicate that some of these mutations may have resulted from recombination.

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Year:  2002        PMID： 12881645     DOI： 10.1023/a:1020996529014

Source DB:  PubMed          Journal:  Virus Genes        ISSN： 0920-8569            Impact factor:   2.332


  11 in total

1.  The reduced virulence of the thymotropic Moloney murine leukemia virus derivative MoMuLV-TB is mapped to 11 mutations within the U3 region of the long terminal repeat.

Authors:  P H Yuen; P F Szurek
Journal:  J Virol       Date:  1989-02       Impact factor: 5.103

2.  Evidence for helper independent murine sarcoma virus. I. Segregation of replication-defective and transformation-defective viruses.

Authors:  J Ball; J A McCarter; S M Sunderland
Journal:  Virology       Date:  1973-11       Impact factor: 3.616

3.  A virus-induced rhabdomyosarcoma of mice.

Authors:  J B Moloney
Journal:  Natl Cancer Inst Monogr       Date:  1966-09

4.  Rapid, selective procedure for isolation of spontaneous temperature-sensitive mutants of Moloney leukemia virus.

Authors:  P K Wong; L J Russ; J A McCarter
Journal:  Virology       Date:  1973-02       Impact factor: 3.616

5.  A 1.6-kilobase-pair fragment in the genome of the ts1 mutant of Moloney murine leukemia virus TB that is associated with temperature sensitivity, nonprocessing of Pr80env, and paralytogenesis.

Authors:  P H Yuen; D Malehorn; C Knupp; P K Wong
Journal:  J Virol       Date:  1985-05       Impact factor: 5.103

6.  Nucleotide sequence of Moloney murine leukaemia virus.

Authors:  T M Shinnick; R A Lerner; J G Sutcliffe
Journal:  Nature       Date:  1981 Oct 15-21       Impact factor: 49.962

7.  Nucleotide sequence of the genome of a murine sarcoma virus.

Authors:  C Van Beveren; F van Straaten; J A Galleshaw; I M Verma
Journal:  Cell       Date:  1981-11       Impact factor: 41.582

8.  Substitution of the U3 long terminal repeat region of the neurotropic Cas-Br-E retrovirus affects its disease-inducing potential.

Authors:  Y Paquette; D G Kay; E Rassart; Y Robitaille; P Jolicoeur
Journal:  J Virol       Date:  1990-08       Impact factor: 5.103

9.  The kissing-loop motif is a preferred site of 5' leader recombination during replication of SL3-3 murine leukemia viruses in mice.

Authors:  A H Lund; J G Mikkelsen; J Schmidt; M Duch; F S Pedersen
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

10.  Development of physical forms of unintegrated retroviral DNA in mouse spinal cord tissue during ts1-induced spongiform encephalomyelopathy: elevated levels of a novel single-stranded form in paralyzed mice.

Authors:  P F Szurek; B R Brooks
Journal:  J Virol       Date:  1995-01       Impact factor: 5.103
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