Literature DB >> 12881342

Amblyopia treatment outcomes after preschool screening v school entry screening: observational data from a prospective cohort study.

C Williams1, K Northstone, R A Harrad, J M Sparrow, I Harvey.   

Abstract

BACKGROUND/AIMS: Preschool screening for amblyopia has controversially been abandoned in some localities within the United Kingdom, on the basis that there is no clear evidence of benefit to support its continuation. Data collected within a birth cohort study were used to examine visual outcomes at 7(1/2) years in children who did or did not receive preschool vision screening.
METHODS: Monocular logMAR visual acuity with and without a pinhole was assessed by orthoptists. Contemporary records were used to identify children who had been offered and/or received preschool screening.
RESULTS: Of 6081 children, 24.9% had been offered preschool screening and 16.7% had attended. The prevalence of amblyopia was approximately 45% lower in the children who received preschool screening than in those who did not (1.1% v 2.0%, p = 0.05). The mean acuity in the worse seeing eyes after patching treatment was better for amblyopic children who received preschool screening than for those who did not; 0.14 v 0.20 logMAR (p <0.001). These effects did not persist in an intention to screen analysis.
CONCLUSIONS: Preschool screening at 37 months was associated with an improved treatment outcome for individuals with amblyopia. However, the improvement was clinically small and disappeared when considering all children offered screening rather than only those who received it. Further research is needed into improving the effectiveness of vision screening for preschool children, while in the interim these data do not conflict with current recommendations for school entry screening by orthoptists.

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Year:  2003        PMID: 12881342      PMCID: PMC1771818          DOI: 10.1136/bjo.87.8.988

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  27 in total

1.  Comparison of preschool vision screening methods in a population with a high prevalence of astigmatism.

Authors:  J M Miller; V Dobson; E M Harvey; D L Sherrill
Journal:  Invest Ophthalmol Vis Sci       Date:  2001-04       Impact factor: 4.799

2.  The cost-effectiveness of screening strategies for amblyopia: a preliminary report.

Authors:  S Schlichtherle; A Gandjour; A Neugebauer; W Rüssmann; K W Lauterbach
Journal:  Strabismus       Date:  2000-12

Review 3.  Screening and surveillance for ophthalmic disorders and visual deficits in children in the United Kingdom.

Authors:  J S Rahi; C Williams; H Bedford; D Elliman
Journal:  Br J Ophthalmol       Date:  2001-03       Impact factor: 4.638

4.  Screening for amblyopia in preschool children: results of a population-based, randomised controlled trial. ALSPAC Study Team. Avon Longitudinal Study of Pregnancy and Childhood.

Authors:  C Williams; R A Harrad; I Harvey; J M Sparrow
Journal:  Ophthalmic Epidemiol       Date:  2001-12       Impact factor: 1.648

5.  The therapy of amblyopia: an analysis comparing the results of amblyopia therapy utilizing two pooled data sets.

Authors:  J T Flynn; G Woodruff; J R Thompson; F Hiscox; W Feuer; J Schiffman; A Corona; L K Smith
Journal:  Trans Am Ophthalmol Soc       Date:  1999

6.  ALSPAC--the Avon Longitudinal Study of Parents and Children. I. Study methodology.

Authors:  J Golding; M Pembrey; R Jones
Journal:  Paediatr Perinat Epidemiol       Date:  2001-01       Impact factor: 3.980

Review 7.  Postnatal development of the visual cortex and the influence of environment.

Authors:  T N Wiesel
Journal:  Nature       Date:  1982-10-14       Impact factor: 49.962

8.  Cost-effectiveness of orthoptic screening in kindergarten: a decision-analytic model.

Authors:  H H König; J C Barry; R Leidl; E Zrenner
Journal:  Strabismus       Date:  2000-06

9.  Economic evaluation of different methods of screening for amblyopia in kindergarten.

Authors:  Hans-Helmut König; Jean-Cyriaque Barry
Journal:  Pediatrics       Date:  2002-04       Impact factor: 7.124

10.  Anisometropia in children: analysis of a hospital population.

Authors:  J de Vries
Journal:  Br J Ophthalmol       Date:  1985-07       Impact factor: 4.638

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  28 in total

Review 1.  Vision screening in preschool children: do the data support universal screening?

Authors:  Wolf A Lagrèze
Journal:  Dtsch Arztebl Int       Date:  2010-07-12       Impact factor: 5.594

2.  The negative impact of amblyopia from a population perspective: untreated amblyopia almost doubles the lifetime risk of bilateral visual impairment.

Authors:  Josefin Nilsso
Journal:  Br J Ophthalmol       Date:  2007-11       Impact factor: 4.638

3.  Prevalence, causes and associations of amblyopia in year 1 students in Central China : The Anyang childhood eye study (ACES).

Authors:  Jing Fu; Shi Ming Li; Si Yuan Li; Jin Ling Li; He Li; Bi Dan Zhu; Zhou Yang; Lei Li; Ning Li Wang
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2013-11-08       Impact factor: 3.117

Review 4.  Amblyopia.

Authors:  Stephanie West; Cathy Williams
Journal:  BMJ Clin Evid       Date:  2011-06-30

Review 5.  Amblyopia.

Authors:  Cathy Williams
Journal:  BMJ Clin Evid       Date:  2009-09-16

6.  Interactive binocular treatment (I-BiT) for amblyopia: results of a pilot study of 3D shutter glasses system.

Authors:  N Herbison; S Cobb; R Gregson; I Ash; R Eastgate; J Purdy; T Hepburn; D MacKeith; A Foss
Journal:  Eye (Lond)       Date:  2013-06-28       Impact factor: 3.775

7.  Assessment of a modification of Brückner's test as a screening modality for anisometropia and strabismus.

Authors:  Abadan Khan Amitava; D Kewlani; Z Khan; A Razzak
Journal:  Oman J Ophthalmol       Date:  2010-09

8.  Prevalence of amblyopia and strabismus in white and African American children aged 6 through 71 months the Baltimore Pediatric Eye Disease Study.

Authors:  David S Friedman; Michael X Repka; Joanne Katz; Lydia Giordano; Josephine Ibironke; Patricia Hawse; James M Tielsch
Journal:  Ophthalmology       Date:  2009-09-16       Impact factor: 12.079

Review 9.  Amblyopia and binocular vision.

Authors:  Eileen E Birch
Journal:  Prog Retin Eye Res       Date:  2012-11-29       Impact factor: 21.198

Review 10.  Effectiveness of screening preschool children for amblyopia: a systematic review.

Authors:  Christine Schmucker; Robert Grosselfinger; Rob Riemsma; Gerd Antes; Stefan Lange; Wolf Lagrèze; Jos Kleijnen
Journal:  BMC Ophthalmol       Date:  2009-07-16       Impact factor: 2.209

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