| Literature DB >> 12880353 |
Joanna Malicka1, Ignacy Gryczynski, Chris D Geddes, Joseph R Lakowicz.
Abstract
Indocyanine green (ICG) is widely used in medical imaging and testing. Its complex spectral behavior and low quantum yield limits some applications. We show that proximity of ICG to a metallic silver particle increases its intensity approximately 20-fold and decreases the decay time. Since the rate of photobleaching is not increased, our results suggest that ICG-silver particle complexes can yield at least 20-fold more photons per ICG molecule for improved medical imaging. (c) 2003 Society of Photo-Optical Instrumentation Engineers.Entities:
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Year: 2003 PMID: 12880353 PMCID: PMC6942523 DOI: 10.1117/1.1578643
Source DB: PubMed Journal: J Biomed Opt ISSN: 1083-3668 Impact factor: 3.170