| Literature DB >> 12880322 |
Erik Larsen1, Arsalan Kharazmi, Lars P Christensen, S Brøgger Christensen.
Abstract
The galactolipid (2S)-1,2-di-O-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]-3-O-beta-d-galactopyranosyl glycerol (1) isolated from dried and milled fruits of Rosa canina by bioassay-guided fractionation is an antiinflammatory agent with inhibitory effects on chemotaxis of human peripheral blood neutrophils in vitro. The inhibition of cell migration is not related to toxicity. The presence of 1 in rose hips may explain the clinically observed antiinflammatory properties of rose hip herbal remedies.Entities:
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Year: 2003 PMID: 12880322 DOI: 10.1021/np0300636
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050