Literature DB >> 12880312

cis,cis-Germacranolides and melampolides from Mikania thapsoides.

César A N Catalán1, María Del R Cuenca, Luis R Hernández, Pedro Joseph-Nathan.   

Abstract

The aerial parts of Mikania thapsoides afforded six new cis,cis-germacranolide-type sesquiterpene lactones (1-6), of which three (1-3) have an unusual 3,4-epoxy function, and also afforded two new melampolides (7 and 8). All compounds have a trans C-8 lactone ring closure. Their structures were elucidated using 1D and 2D NMR measurements, and the absolute configuration of 1 was determined using the Mosher ester method.

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Year:  2003        PMID: 12880312     DOI: 10.1021/np030055p

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  3 in total

1.  Antiplasmodial Sesquiterpenoid Lactones from Trichospira verticillata: Structure Elucidation by Spectroscopic Methods and Comparison of Experimental and Calculated ECD Data.

Authors:  Yongle Du; Kirk C Pearce; Yumin Dai; Priscilla Krai; Seema Dalal; Maria B Cassera; Michael Goetz; T Daniel Crawford; David G I Kingston
Journal:  J Nat Prod       Date:  2017-05-02       Impact factor: 4.050

2.  New Techniques of Structure Elucidation for Sesquiterpenes.

Authors:  Julio C Pardo-Novoa; Carlos M Cerda-García-Rojas
Journal:  Prog Chem Org Nat Prod       Date:  2021

3.  In vitro evaluation of antiprotozoal and antiviral activities of extracts from Argentinean Mikania species.

Authors:  Laura C Laurella; Fernanda M Frank; Andrea Sarquiz; María R Alonso; Gustavo Giberti; Lucia Cavallaro; Cesar A Catalán; Silvia I Cazorla; Emilio Malchiodi; Virginia S Martino; Valeria P Sülsen
Journal:  ScientificWorldJournal       Date:  2012-07-31
  3 in total

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