Literature DB >> 12879450

Human genetic diversity: Lewontin's fallacy.

A W F Edwards1.   

Abstract

In popular articles that play down the genetical differences among human populations, it is often stated that about 85% of the total genetical variation is due to individual differences within populations and only 15% to differences between populations or ethnic groups. It has therefore been proposed that the division of Homo sapiens into these groups is not justified by the genetic data. This conclusion, due to R.C. Lewontin in 1972, is unwarranted because the argument ignores the fact that most of the information that distinguishes populations is hidden in the correlation structure of the data and not simply in the variation of the individual factors. The underlying logic, which was discussed in the early years of the last century, is here discussed using a simple genetical example. Copyright 2003 Wiley Periodicals, Inc.

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Year:  2003        PMID: 12879450     DOI: 10.1002/bies.10315

Source DB:  PubMed          Journal:  Bioessays        ISSN: 0265-9247            Impact factor:   4.345


  36 in total

1.  The structure of cross-cultural musical diversity.

Authors:  Tom Rzeszutek; Patrick E Savage; Steven Brown
Journal:  Proc Biol Sci       Date:  2011-11-09       Impact factor: 5.349

Review 2.  A population-genetic perspective on the similarities and differences among worldwide human populations.

Authors:  Noah A Rosenberg
Journal:  Hum Biol       Date:  2011-12       Impact factor: 0.553

3.  A family tree in every gene.

Authors:  Armand Marie Leroi
Journal:  J Genet       Date:  2005-04       Impact factor: 1.166

4.  Genetic similarities within and between human populations.

Authors:  D J Witherspoon; S Wooding; A R Rogers; E E Marchani; W S Watkins; M A Batzer; L B Jorde
Journal:  Genetics       Date:  2007-03-04       Impact factor: 4.562

5.  Using allele sharing distance for detecting human population stratification.

Authors:  Xiaoyi Gao; Eden R Martin
Journal:  Hum Hered       Date:  2009-06-11       Impact factor: 0.444

Review 6.  Statistical methods for evolutionary trees.

Authors:  A W F Edwards
Journal:  Genetics       Date:  2009-09       Impact factor: 4.562

7.  Linkage disequilibrium matches forensic genetic records to disjoint genomic marker sets.

Authors:  Michael D Edge; Bridget F B Algee-Hewitt; Trevor J Pemberton; Jun Z Li; Noah A Rosenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2017-05-15       Impact factor: 11.205

Review 8.  Recent advances in the study of fine-scale population structure in humans.

Authors:  John Novembre; Benjamin M Peter
Journal:  Curr Opin Genet Dev       Date:  2016-09-20       Impact factor: 5.578

9.  Proportioning whole-genome single-nucleotide-polymorphism diversity for the identification of geographic population structure and genetic ancestry.

Authors:  Oscar Lao; Kate van Duijn; Paula Kersbergen; Peter de Knijff; Manfred Kayser
Journal:  Am J Hum Genet       Date:  2006-02-14       Impact factor: 11.025

10.  A highly efficient multi-core algorithm for clustering extremely large datasets.

Authors:  Johann M Kraus; Hans A Kestler
Journal:  BMC Bioinformatics       Date:  2010-04-06       Impact factor: 3.169

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