| Literature DB >> 12879310 |
Alistair J Easterfield1, J Andrew Bradley, Eleanor M Bolton.
Abstract
The rat major histocompatibility complex loci RT1-B and RT1-D are equivalent to the human leucocyte antigens HLA-DQ and HLA-DR respectively. Here we describe the complementary DNA (cDNA) sequence encoding the alpha and beta chains of both the RT1-B and RT1-D locus genes of the rat RT1u haplotype. We have found entire sequence identity between five different inbred rat strains of the RT1u haplotype, which differs from previously published, incomplete sequences. This information is of considerable value for experimental studies of transplantation immunity and autoimmune disease.Entities:
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Year: 2003 PMID: 12879310 DOI: 10.1007/s00251-003-0584-7
Source DB: PubMed Journal: Immunogenetics ISSN: 0093-7711 Impact factor: 2.846