| Literature DB >> 12878546 |
George A Syrogiannopoulos1, Ioanna N Grivea, Lois M Ednie, Bülent Bozdogan, George D Katopodis, Nicholas G Beratis, Todd A Davies, Peter C Appelbaum.
Abstract
Erythromycin-resistant Streptococcus pneumoniae isolates from young carriers were tested for their antimicrobial susceptibility; additionally, inducibility of macrolide and clindamycin resistance was investigated in pneumococci carrying erm(A), erm(B), or mef(A). Of 125 strains tested, 101 (81%) were multidrug resistant. Different levels of induction were observed with erythromycin, miocamycin, and clindamycin in erm(B) strains; however, in erm(A) strains only erythromycin was an inducer. Induction did not affect macrolide MICs in mef(A) strains.Entities:
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Year: 2003 PMID: 12878546 PMCID: PMC166089 DOI: 10.1128/AAC.47.8.2699-2702.2003
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191