Literature DB >> 12878538

Alpha-defensin 1 (human neutrophil protein 1) as an antichemotactic agent for human polymorphonuclear leukocytes.

P S Grutkoski1, C T Graeber, Y P Lim, A Ayala, H H Simms.   

Abstract

Medium conditioned by tumor necrosis factor alpha (TNF-alpha)-stimulated polymorphonuclear leukocytes (PMN) (CM-TNF) suppresses PMN migration. Therefore, we wished to identify the agent(s) in CM-TNF that mediated antichemotactic activity. CM-TNF was fractionated by high-performance liquid chromatography, and one fraction with antichemotactic activity contained the bactericidal protein human neutrophil protein 1 (HNP-1). We showed that HNP-1 suppresses PMN migration to formyl-methionyl-leucyl-phenylalanine but not to interleukin 8.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12878538      PMCID： PMC166108          DOI： 10.1128/AAC.47.8.2666-2668.2003

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  18 in total

1.  Tumor necrosis factor-alpha-stimulated polymorphonuclear leukocytes suppress migration and bactericidal activity of polymorphonuclear leukocytes in a paracrine manner.

Authors:  Patricia S Grutkoski; Ron D'Amico; Alfred Ayala; H Hank Simms
Journal:  Crit Care Med       Date:  2002-03       Impact factor: 7.598

2.  Signalling by CXC-chemokine receptors 1 and 2 expressed in CHO cells: a comparison of calcium mobilization, inhibition of adenylyl cyclase and stimulation of GTPgammaS binding induced by IL-8 and GROalpha.

Authors:  D A Hall; I J Beresford; C Browning; H Giles
Journal:  Br J Pharmacol       Date:  1999-02       Impact factor: 8.739

3.  Evaluation of the effects of defensins on neutrophil functions.

Authors:  S Yomogida; I Nagaoka; K Saito; T Yamashita
Journal:  Inflamm Res       Date:  1996-02       Impact factor: 4.575

4.  Evidence of zeta protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis.

Authors:  C Laudanna; D Mochly-Rosen; T Liron; G Constantin; E C Butcher
Journal:  J Biol Chem       Date:  1998-11-13       Impact factor: 5.157

5.  Monocyte-chemotactic activity of defensins from human neutrophils.

Authors:  M C Territo; T Ganz; M E Selsted; R Lehrer
Journal:  J Clin Invest       Date:  1989-12       Impact factor: 14.808

6.  Human C-reactive protein inhibits neutrophil chemotaxis in vitro: possible implications for the adult respiratory distress syndrome.

Authors:  R R Kew; T M Hyers; R O Webster
Journal:  J Lab Clin Med       Date:  1990-03

7.  Heterologous desensitization of IL-8-mediated chemotaxis in human neutrophils by a cell-binding fragment of fibronectin.

Authors:  K J Stanton; M B Frewin; P W Gudewicz
Journal:  J Leukoc Biol       Date:  1999-04       Impact factor: 4.962

8.  Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils.

Authors:  O Chertov; D F Michiel; L Xu; J M Wang; K Tani; W J Murphy; D L Longo; D D Taub; J J Oppenheim
Journal:  J Biol Chem       Date:  1996-02-09       Impact factor: 5.157

9.  Surfactant protein A differentially regulates peripheral and inflammatory neutrophil chemotaxis.

Authors:  Trista L Schagat; Jessica A Wofford; Kelly E Greene; Jo Rae Wright
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2002-08-30       Impact factor: 5.464

10.  Diverging signal transduction pathways activated by interleukin 8 (IL-8) and related chemokines in human neutrophils. IL-8 and Gro-alpha differentially stimulate calcium influx through IL-8 receptors A and B.

Authors:  B B Damaj; S R McColl; K Neote; C A Hébert; P H Naccache
Journal:  J Biol Chem       Date:  1996-08-23       Impact factor: 5.157
View more
  6 in total

1.  Alpha-defensin DEFA1A3 gene copy number elevation in Danish Crohn's disease patients.

Authors:  Cathrine Jespersgaard; Peder Fode; Marianne Dybdahl; Ida Vind; Ole Haagen Nielsen; Claudio Csillag; Pia Munkholm; Ben Vainer; Lene Riis; Margarita Elkjaer; Natalia Pedersen; Elisabeth Knudsen; Paal Skytt Andersen
Journal:  Dig Dis Sci       Date:  2011-06-24       Impact factor: 3.199

2.  Effects of Niacin on Resistance to Enterotoxigenic Escherichia coli Infection in Weaned Piglets.

Authors:  Rui Zhen; Junsen Feng; Dongsheng He; Yibo Chen; Tianbao Chen; Weiyou Cai; Yunxia Xiong; Yueqin Qiu; Zongyong Jiang; Li Wang; Hongbo Yi
Journal:  Front Nutr       Date:  2022-04-29

3.  Analysis of neutrophil-derived antimicrobial peptides in gingival crevicular fluid suggests importance of cathelicidin LL-37 in the innate immune response against periodontogenic bacteria.

Authors:  M Puklo; A Guentsch; P S Hiemstra; S Eick; J Potempa
Journal:  Oral Microbiol Immunol       Date:  2008-08

Review 4.  Alarmins link neutrophils and dendritic cells.

Authors:  De Yang; Gonzalo de la Rosa; Poonam Tewary; Joost J Oppenheim
Journal:  Trends Immunol       Date:  2009-08-21       Impact factor: 16.687

Review 5.  Immunomodulatory properties of defensins and cathelicidins.

Authors:  D M E Bowdish; D J Davidson; R E W Hancock
Journal:  Curr Top Microbiol Immunol       Date:  2006       Impact factor: 4.291

Review 6.  Avian defensins.

Authors:  Albert van Dijk; Edwin J A Veldhuizen; Henk P Haagsman
Journal:  Vet Immunol Immunopathol       Date:  2008-02-01       Impact factor: 2.046
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.