Literature DB >> 12877889

Transfusion-related acute lung injury (TRALI) following platelet transfusion in a patient receiving high-dose interleukin-2 for treatment of metastatic renal cell carcinoma.

Bruno C Medeiros1, Karen E Kogel, Madeleine A Kane.   

Abstract

Transfusion-related acute lung injury (TRALI) is an uncommon life-threatening complication of hemotherapy. It is hypothesized to be the result of two independent insults: the first related to the clinical status of the patient and the second to the infusion of biologic response modifiers within blood components. We present a case of TRALI in a patient who received high-dose Interleukin-2 (IL-2) as treatment for metastatic renal cell carcinoma, where IL-2 is speculated to have been the first insult and transfusion of platelet concentrate the second. This is the first reported case of TRALI complicating treatment with high-dose immunotherapy.

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Year:  2003        PMID： 12877889     DOI： 10.1016/S1473-0502(03)00094-6

Source DB:  PubMed          Journal:  Transfus Apher Sci        ISSN： 1473-0502            Impact factor:   1.764


  5 in total

1.  Transfusion-related acute lung injury (TRALI)--an important, severe transfusion-related complication.

Authors:  Marco Bueter; Andreas Thalheimer; Frank Schuster; Markus Böck; Christina von Erffa; Detlef Meyer; Martin Fein
Journal:  Langenbecks Arch Surg       Date:  2006-08-15       Impact factor: 3.445

2.  Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury.

Authors:  Samina Yasmin Khan; Marguerite R Kelher; Joanna M Heal; Neil Blumberg; Lynn K Boshkov; Richard Phipps; Kelly F Gettings; Nathan J McLaughlin; Christopher C Silliman
Journal:  Blood       Date:  2006-06-13       Impact factor: 22.113

Review 3.  The role of neutrophils in the pathogenesis of transfusion-related acute lung injury.

Authors:  Yoke Lin Fung; Christopher C Silliman
Journal:  Transfus Med Rev       Date:  2009-10

Review 4.  Transfusion-related acute lung injury (TRALI): current concepts and misconceptions.

Authors:  Christopher C Silliman; Yoke Lin Fung; J Bradley Ball; Samina Y Khan
Journal:  Blood Rev       Date:  2009-08-20       Impact factor: 8.250

5.  Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model.

Authors:  Marguerite R Kelher; Tomhiko Masuno; Ernest E Moore; Sagar Damle; Xianzhong Meng; Yong Song; Xiayuan Liang; Jerry Niedzinski; Steven S Geier; Samina Y Khan; Fabia Gamboni-Robertson; Christopher C Silliman
Journal:  Blood       Date:  2009-01-08       Impact factor: 22.113
  5 in total

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