Literature DB >> 12877552

Antibacterial coumarins from Angelica gigas roots.

Sanghyun Lee1, Dong-Sun Shin, Ju Sun Kim, Ki-Bong Oh, Sam Sik Kang.   

Abstract

Systematic fractionation of Angelica gigas roots led to the isolation of linear furano(pyrano)coumarins such as bergapten (1), decursinol angelate (2), decursin (3), nodakenetin (4) and nodakenin (5). The antibacterial activities of those compounds against pathogenic bacteria were investigated. Among the compounds tested, decursinol angelate (2) and decursin (3) exhibited significant antibacterial activity against Bacillus subtilis with the minimum inhibitory concentrations (MICs) of 50 and 12.5 microg/mL, respectively.

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Year:  2003        PMID： 12877552     DOI： 10.1007/bf02976860

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  14 in total

Review 1.  Enantiomeric natural products: occurrence and biogenesis.

Authors:  Jennifer M Finefield; David H Sherman; Martin Kreitman; Robert M Williams
Journal:  Angew Chem Int Ed Engl       Date:  2012-05-03       Impact factor: 15.336

2.  Overexpression of cinnamate 4-hydroxylase gene enhances biosynthesis of decursinol angelate in Angelica gigas hairy roots.

Authors:  Nam Il Park; Jee Hee Park; Sang Un Park
Journal:  Mol Biotechnol       Date:  2012-02       Impact factor: 2.695

3.  Single-dose Intravenous Injection Toxicity of Water-soluble Danggui Pharmacopuncture (WDP) in Sprague-Dawley Rats.

Authors:  Sunju Park; Hae-Mo Park; Seung-Ho Sun
Journal:  J Pharmacopuncture       Date:  2018-06-30

4.  Analysis of fluorescence quenching of coumarin derivatives by 4-hydroxy-TEMPO in aqueous solution.

Authors:  Krzysztof Żamojć; Wiesław Wiczk; Bartłomiej Zaborowski; Dagmara Jacewicz; Lech Chmurzyński
Journal:  J Fluoresc       Date:  2013-12-15       Impact factor: 2.217

5.  Potentiation of decursinol angelate on pentobarbital-induced sleeping behaviors via the activation of GABAA-ergic systems in rodents.

Authors:  Jae Hoon Woo; Tae-Woo Ha; Jae-Seon Kang; Jin Tae Hong; Ki-Wan Oh
Journal:  Korean J Physiol Pharmacol       Date:  2016-12-21       Impact factor: 2.016

6.  Decursin inhibits retinal neovascularization via suppression of VEGFR-2 activation.

Authors:  Jeong Hun Kim; Jin Hyoung Kim; You Mie Lee; Eun-Mi Ahn; Kyu-Won Kim; Young Suk Yu
Journal:  Mol Vis       Date:  2009-09-12       Impact factor: 2.367

7.  Decursin Isolated from Angelica gigas Nakai Rescues PC12 Cells from Amyloid β-Protein-Induced Neurotoxicity through Nrf2-Mediated Upregulation of Heme Oxygenase-1: Potential Roles of MAPK.

Authors:  Li Li; Ji-Kun Du; Li-Yi Zou; Tie Wu; Yong-Woo Lee; Yong-Ho Kim
Journal:  Evid Based Complement Alternat Med       Date:  2013-05-09       Impact factor: 2.629

8.  Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells.

Authors:  Cheng Jiang; Junming Guo; Zhe Wang; Bingxiu Xiao; Hyo-Jung Lee; Eun-Ok Lee; Sung-Hoon Kim; Junxuan Lu
Journal:  Breast Cancer Res       Date:  2007       Impact factor: 6.466

9.  High-performance liquid chromatography determination and pharmacokinetics of coumarin compounds after oral administration of Samul-Tang to rats.

Authors:  Youn-Hwan Hwang; Won-Kyung Cho; Doorye Jang; Jeong-Ho Ha; Jin Yeul Ma
Journal:  Pharmacogn Mag       Date:  2014-01       Impact factor: 1.085

10.  In vitro antibacterial activity of Tabernaemontana alternifolia (Roxb) stem bark aqueous extracts against clinical isolates of methicillin resistant Staphylococcus aureus.

Authors:  Nachiket P Marathe; Mandar H Rasane; Himanshu Kumar; Ankur A Patwardhan; Yogesh S Shouche; Sham S Diwanay
Journal:  Ann Clin Microbiol Antimicrob       Date:  2013-09-25       Impact factor: 3.944
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