Literature DB >> 12875925

Elaboration of laboratory strains of Ebola virus and study of pathophysiological reactions of animals inoculated with these strains.

A A Chepurnov1, N M Zubavichene, A A Dadaeva.   

Abstract

Selective passages in animals and cell cultures were used to produce a set of Ebola virus (EBO) laboratory strains with changed virulence for some animal genera. Comparative study of the genomes of wild-type EBO and selected variants formed the basis for studying the molecular causes of EBO virulence. Investigation of pathophysiological reactions of the animals inoculated with these strains allowed some key factors in Ebola fever pathogenesis to be determined.

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Year:  2003        PMID： 12875925     DOI： 10.1016/s0001-706x(03)00122-0

Source DB:  PubMed          Journal:  Acta Trop        ISSN： 0001-706X            Impact factor:   3.112


  5 in total

1.  Evaluation of perceived threat differences posed by filovirus variants.

Authors:  Jens H Kuhn; Lori E Dodd; Victoria Wahl-Jensen; Sheli R Radoshitzky; Sina Bavari; Peter B Jahrling
Journal:  Biosecur Bioterror       Date:  2011-11-09

2.  Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae.

Authors:  Jens H Kuhn; Yiming Bao; Sina Bavari; Stephan Becker; Steven Bradfute; J Rodney Brister; Alexander A Bukreyev; Yíngyún Caì; Kartik Chandran; Robert A Davey; Olga Dolnik; John M Dye; Sven Enterlein; Jean-Paul Gonzalez; Pierre Formenty; Alexander N Freiberg; Lisa E Hensley; Anna N Honko; Georgy M Ignatyev; Peter B Jahrling; Karl M Johnson; Hans-Dieter Klenk; Gary Kobinger; Matthew G Lackemeyer; Eric M Leroy; Mark S Lever; Loreen L Lofts; Elke Mühlberger; Sergey V Netesov; Gene G Olinger; Gustavo Palacios; Jean L Patterson; Janusz T Paweska; Louise Pitt; Sheli R Radoshitzky; Elena I Ryabchikova; Erica Ollmann Saphire; Aleksandr M Shestopalov; Sophie J Smither; Nancy J Sullivan; Robert Swanepoel; Ayato Takada; Jonathan S Towner; Guido van der Groen; Viktor E Volchkov; Victoria Wahl-Jensen; Travis K Warren; Kelly L Warfield; Manfred Weidmann; Stuart T Nichol
Journal:  Arch Virol       Date:  2013-01-29       Impact factor: 2.574

3.  Molecular determinants of Ebola virus virulence in mice.

Authors:  Hideki Ebihara; Ayato Takada; Darwyn Kobasa; Steven Jones; Gabriele Neumann; Steven Theriault; Mike Bray; Heinz Feldmann; Yoshihiro Kawaoka
Journal:  PLoS Pathog       Date:  2006-07       Impact factor: 6.823

4.  Elucidating variations in the nucleotide sequence of Ebola virus associated with increasing pathogenicity.

Authors:  Stuart D Dowall; David A Matthews; Isabel Garcia-Dorival; Irene Taylor; John Kenny; Christiane Hertz-Fowler; Neil Hall; Kara Corbin-Lickfett; Cyril Empig; Kyle Schlunegger; John N Barr; Miles W Carroll; Roger Hewson; Julian A Hiscox
Journal:  Genome Biol       Date:  2014       Impact factor: 13.583

Review 5.  Adapted Lethality: What We Can Learn from Guinea Pig-Adapted Ebola Virus Infection Model.

Authors:  S V Cheresiz; E A Semenova; A A Chepurnov
Journal:  Adv Virol       Date:  2016-02-18
  5 in total

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