AIMS: This study reports mode, timing and predictive factors of recurrence after curative surgery for cardia cancer. METHODS: A prospective study in a series of 92 curatively (R0) resected patients from 1988 to 2002. RESULTS: The 5-year recurrence rate was 71%. Lymph node involvement was the only predictor of recurrence. No patients with more than 6 metastatic nodes were free from relapse 2 years after surgery. Locoregional, peritoneal and haematogenous relapses showed a similar median recurrence time (12, 10 and 12 months, respectively), 80% occurred within 24 months. CONCLUSIONS: Few patients can be cured by surgery, lymph nodal involvement is the only predictor of recurrence.
AIMS: This study reports mode, timing and predictive factors of recurrence after curative surgery for cardia cancer. METHODS: A prospective study in a series of 92 curatively (R0) resected patients from 1988 to 2002. RESULTS: The 5-year recurrence rate was 71%. Lymph node involvement was the only predictor of recurrence. No patients with more than 6 metastatic nodes were free from relapse 2 years after surgery. Locoregional, peritoneal and haematogenous relapses showed a similar median recurrence time (12, 10 and 12 months, respectively), 80% occurred within 24 months. CONCLUSIONS: Few patients can be cured by surgery, lymph nodal involvement is the only predictor of recurrence.
Authors: Harry H Yoon; Maliha Khan; Qian Shi; Stephen D Cassivi; Tsung-Teh Wu; J Fernando Quevedo; Patrick A Burch; Frank A Sinicrope; Robert B Diasio Journal: Mayo Clin Proc Date: 2010-12 Impact factor: 7.616
Authors: Nikolaos Charalampakis; Graciela M Nogueras González; Elena Elimova; Roopma Wadhwa; Hironori Shiozaki; Yusuke Shimodaira; Mariela A Blum; Jane E Rogers; Kazuto Harada; Aurelio Matamoros; Tara Sagebiel; Prajnan Das; Bruce D Minsky; Jeffrey H Lee; Brian Weston; Manoop S Bhutani; Jeannelyn S Estrella; Brian D Badgwell; Jaffer A Ajani Journal: Oncology Date: 2016-04-06 Impact factor: 2.935