Josep Bonet1, Ramon Coll, Enrique Rocha, Ramón Romero. 1. Nephrology Department and Arterial Hypertension Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain. bonetsol@ns.hugtip.scs.es
Abstract
OBJECTIVE: The aim of this study is to evaluate, in women with grade 1 essential hypertension, the response of cardio-respiratory and blood pressure (BP) after 6 weeks ofsupervised physical exercise (PE) vs only recommended exercise. METHODS:Eighteen consecutive hypertensive women whose BP control was stable were assigned randomly into two exercise groups. Group A including nine patients in an aerobic PE programme supervised by a physiotherapist, aged (mean +/- SD) 35.5 +/- 5.5 years old. Group B, nine patients aged 37.7 +/- 7.2 years old, received only oral and written instructions about the benefits of aerobic PE for controlling BP. We used a treadmill for walking to observe the cardio-respiratory and BP response at the beginning and at the end of the period of exercise training, and the response in all the patients, and to test whether there were any differences between the two groups. RESULTS: There were significant differences in cardio-respiratory parameters in group A, in basal VO2/kg post- vs pre-rehabilitation 27.6 +/- 5.1 vs 23.1 +/- 4.6, change 4.4 +/- 2; O2 pulse 10.9 +/- 0.9 vs 10.4 +/- 1.6, varied 0.5 +/- 0.1; furthermore we observed heart rate 73.3 +/- 12.37 vs 86.6 +/- 12.8, change -13.4 +/- 12.1 and metabolic equivalents of oxygen 9 +/- 1.2 vs 6.6 +/- 2.7, change 2.5 +/- 1.6, while in BP in group A, the differences were 153.1 +/- 7.1 vs 148.8 +/- 13.6, change -6.3 +/- 0.7 mm/g, p < 0.01 between pre- and post-rehabilitation. There were also significant differences between pre- and post-rehabilitation in group A in systolic BP 153 +/- 7.3 vs 135.1 +/- 16, change -18.1 +/- 4.1, p < 0.001 and diastolic BP 92.6 +/- 10.1 vs 83.5 +/- 9.1, change -9 +/- 4, p < 0.05; no change in group B. Finally, an improvement was observed in pulse pressure post-rehabilitation in group A 61.4 +/- 15.2 vs 51.6 +/- 11.4, change -9.8 +/- 3.9 vs group B 59.4 +/- 11.2 vs 59.3 +/- 10.6, only -0.1 +/- 0.8, p < 0.001. CONCLUSIONS: These results suggest that supervised PE in hypertensive women significantly improves cardio-respiratory and BP values, as well as vascular adaptability.
RCT Entities:
OBJECTIVE: The aim of this study is to evaluate, in women with grade 1 essential hypertension, the response of cardio-respiratory and blood pressure (BP) after 6 weeks of supervised physical exercise (PE) vs only recommended exercise. METHODS: Eighteen consecutive hypertensivewomen whose BP control was stable were assigned randomly into two exercise groups. Group A including nine patients in an aerobic PE programme supervised by a physiotherapist, aged (mean +/- SD) 35.5 +/- 5.5 years old. Group B, nine patients aged 37.7 +/- 7.2 years old, received only oral and written instructions about the benefits of aerobic PE for controlling BP. We used a treadmill for walking to observe the cardio-respiratory and BP response at the beginning and at the end of the period of exercise training, and the response in all the patients, and to test whether there were any differences between the two groups. RESULTS: There were significant differences in cardio-respiratory parameters in group A, in basal VO2/kg post- vs pre-rehabilitation 27.6 +/- 5.1 vs 23.1 +/- 4.6, change 4.4 +/- 2; O2 pulse 10.9 +/- 0.9 vs 10.4 +/- 1.6, varied 0.5 +/- 0.1; furthermore we observed heart rate 73.3 +/- 12.37 vs 86.6 +/- 12.8, change -13.4 +/- 12.1 and metabolic equivalents of oxygen 9 +/- 1.2 vs 6.6 +/- 2.7, change 2.5 +/- 1.6, while in BP in group A, the differences were 153.1 +/- 7.1 vs 148.8 +/- 13.6, change -6.3 +/- 0.7 mm/g, p < 0.01 between pre- and post-rehabilitation. There were also significant differences between pre- and post-rehabilitation in group A in systolic BP 153 +/- 7.3 vs 135.1 +/- 16, change -18.1 +/- 4.1, p < 0.001 and diastolic BP 92.6 +/- 10.1 vs 83.5 +/- 9.1, change -9 +/- 4, p < 0.05; no change in group B. Finally, an improvement was observed in pulse pressure post-rehabilitation in group A 61.4 +/- 15.2 vs 51.6 +/- 11.4, change -9.8 +/- 3.9 vs group B 59.4 +/- 11.2 vs 59.3 +/- 10.6, only -0.1 +/- 0.8, p < 0.001. CONCLUSIONS: These results suggest that supervised PE in hypertensivewomen significantly improves cardio-respiratory and BP values, as well as vascular adaptability.
Authors: Ling-Ling Lee; Caroline A Mulvaney; Yoko Kin Yoke Wong; Edwin Sy Chan; Michael C Watson; Hui-Hsin Lin Journal: Cochrane Database Syst Rev Date: 2021-02-24