Literature DB >> 1287477

Estrogen-induced synthesis of uterine proteins declines during aging.

M K Thakur1, J Kaur.   

Abstract

The synthesis of total cellular as well as acid-soluble nuclear proteins and estrogen receptor is high in the uteri of young (22 weeks) and decreases to half in old (104 weeks) rats. Administration of estrogen induces the synthesis of these proteins significantly in young but shows no remarkable effect in old rats. Interestingly, a specific cytosolic protein of 45 kDa is stimulated about two-fold after estrogen injection in young but not in old rats. These findings further establish the reduced responsiveness of uterus to estrogen in old age.

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Year:  1992        PMID： 1287477     DOI： 10.1007/bf01006397

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  16 in total

1.  Analysis in vitro of uterine estrogen receptor conformation of young and old rats.

Authors:  M K Tnakur; J Kaur
Journal:  Mol Cell Biochem       Date:  1991-07-10       Impact factor: 3.396

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

Review 3.  Ovarian steroid action on gene expression: mechanisms and models.

Authors:  C Rories; T C Spelsberg
Journal:  Annu Rev Physiol       Date:  1989       Impact factor: 19.318

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

Review 5.  Molecular mechanism of steroid hormone action during aging. A review.

Authors:  M K Thakur
Journal:  Mech Ageing Dev       Date:  1988-11-14       Impact factor: 5.432

Review 6.  Protein synthesis and degradation during aging and senescence.

Authors:  S C Makrides
Journal:  Biol Rev Camb Philos Soc       Date:  1983-08

7.  Identification of the major component of the estrogen-induced protein of rat uterus as the BB isozyme of creatine kinase.

Authors:  N A Reiss; A M Kaye
Journal:  J Biol Chem       Date:  1981-06-10       Impact factor: 5.157

8.  Isolated uterine nuclei and cytosol receptors of aged rats exhibit impaired estrogenic stimulation of RNA polymerase II.

Authors:  M Haji; R S Chuknyiska; G S Roth
Journal:  Proc Natl Acad Sci U S A       Date:  1984-12       Impact factor: 11.205

9.  Effect of post-synthetic modifications of proteins on the binding of estrogen-receptor complex to uterine nuclei of aging rats.

Authors:  J Kaur; M K Thakur
Journal:  Mol Biol Rep       Date:  1990-11       Impact factor: 2.316

10.  Steroid-induced proteins in human endometrium.

Authors:  S Iacobelli; P Marchetti; E Bartoccioni; V Natoli; G Scambia; A M Kaye
Journal:  Mol Cell Endocrinol       Date:  1981-09       Impact factor: 4.102
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  1 in total

1.  The effect of Momordica charantia intake on the estrogen receptors ESRα/ESRβ gene levels and apoptosis on uterine tissue in ovariectomy rats.

Authors:  Ozge Cevik; Hikmet Akpinar; Rabia Oba; Ozlem Tugce Cilingir; Zarife Nigar Ozdemir; Sule Cetinel; Tevfik Yoldemir
Journal:  Mol Biol Rep       Date:  2014-09-25       Impact factor: 2.316
  1 in total

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