| Literature DB >> 12874410 |
Daniel Tarsy1, Diana Apetauerova, Patricia Ryan, Thorkild Norregaard.
Abstract
A 59-year-old woman with levodopa-responsive parkinsonism complicated by motor fluctuations and generalized levodopa dyskinesia underwent bilateral subthalamic deep brain stimulation (STN DBS) 7 years after symptom onset. DBS improved levodopa-responsive upper extremity bradykinesia but aggravated speech, swallowing, and gait. Motor fluctuations were not improved and levodopa dose remained unchanged. Pulse generators were turned off. Clinical features and brain MRI in this case were indicative of multiple system atrophy (MSA). STN DBS is not recommended for patients with MSA.Entities:
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Year: 2003 PMID: 12874410 DOI: 10.1212/01.wnl.0000073986.74883.36
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910