Literature DB >> 12874162

Element of caution: a case of reversible cytopenias associated with excessive zinc supplementation.

Julie A Irving1, Andre Mattman, Gillian Lockitch, Kevin Farrell, Louis D Wadsworth.   

Abstract

Zinc is a common supplement and is widely available as a standard component of many over-the-counter products. A number of reports have identified an association between excessive zinc intake and severe cytopenia. We report a case of zinc-induced copper deficiency in a young adult to illustrate this under-recognized cause of anemia and neutropenia.

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Year:  2003        PMID： 12874162      PMCID： PMC164980     

Source DB:  PubMed          Journal:  CMAJ        ISSN： 0820-3946            Impact factor:   8.262


  18 in total

1.  Dietary reference intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc.

Authors:  P Trumbo; A A Yates; S Schlicker; M Poos
Journal:  J Am Diet Assoc       Date:  2001-03

2.  Zinc-induced anemia and neutropenia in an adolescent.

Authors:  T J Porea; J W Belmont; D H Mahoney
Journal:  J Pediatr       Date:  2000-05       Impact factor: 4.406

3.  Case report of sideroblastic anemia caused by ingestion of coins.

Authors:  A Kumar; A R Jazieh
Journal:  Am J Hematol       Date:  2001-02       Impact factor: 10.047

4.  Efficacy of zinc supplementation in reducing the incidence and prevalence of acute diarrhea--a community-based, double-blind, controlled trial.

Authors:  S Sazawal; R E Black; M K Bhan; S Jalla; A Sinha; N Bhandari
Journal:  Am J Clin Nutr       Date:  1997-08       Impact factor: 7.045

5.  Treatment of four siblings with progressive myoclonus epilepsy of the Unverricht-Lundborg type with N-acetylcysteine.

Authors:  R W Hurd; B J Wilder; W R Helveston; B M Uthman
Journal:  Neurology       Date:  1996-11       Impact factor: 9.910

Review 6.  Copper intake and assessment of copper status.

Authors:  D B Milne
Journal:  Am J Clin Nutr       Date:  1998-05       Impact factor: 7.045

7.  Zinc toxicity following massive coin ingestion.

Authors:  D R Bennett; C J Baird; K M Chan; P F Crookes; C G Bremner; M M Gottlieb; W Y Naritoku
Journal:  Am J Forensic Med Pathol       Date:  1997-06       Impact factor: 0.921

8.  Anaemia and low serum-copper during zinc therapy.

Authors:  K G Porter; D McMaster; M E Elmes; A H Love
Journal:  Lancet       Date:  1977-10-08       Impact factor: 79.321

9.  Zinc-induced copper deficiency in a coin swallower.

Authors:  H A Hassan; C Netchvolodoff; J P Raufman
Journal:  Am J Gastroenterol       Date:  2000-10       Impact factor: 10.864

10.  Copper deficiency masquerading as myelodysplastic syndrome.

Authors:  Xylina T Gregg; Vishnu Reddy; Josef T Prchal
Journal:  Blood       Date:  2002-08-15       Impact factor: 22.113
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  5 in total

1.  Cytopenia and Bone Marrow Dysplasia in a Case of Wilson's Disease.

Authors:  Aarathi R Rau; M Usha; Pooja Mallya; A T K Rau
Journal:  Indian J Hematol Blood Transfus       Date:  2014-09-07       Impact factor: 0.900

Review 2.  Zinc Essentiality, Toxicity, and Its Bacterial Bioremediation: A Comprehensive Insight.

Authors:  Sarfraz Hussain; Maryam Khan; Taha Majid Mahmood Sheikh; Muhammad Zahid Mumtaz; Talha Ali Chohan; Saba Shamim; Yuhong Liu
Journal:  Front Microbiol       Date:  2022-05-31       Impact factor: 6.064

Review 3.  The essential toxin: impact of zinc on human health.

Authors:  Laura M Plum; Lothar Rink; Hajo Haase
Journal:  Int J Environ Res Public Health       Date:  2010-03-26       Impact factor: 3.390

4.  Clonality investigation of morphologically dysplastic hematopoietic cells in myelodysplastic syndrome marrows.

Authors:  Xiao Li; Lingyun Wu; Shaoxu Ying; Chunkang Chang; Quan Pu
Journal:  Int J Hematol       Date:  2008-02-07       Impact factor: 2.490

5.  Enhanced Zinc Intake Protects against Oxidative Stress and Its Consequences in the Brain: A Study in an In Vivo Rat Model of Cadmium Exposure.

Authors:  Małgorzata M Brzóska; Magdalena Kozłowska; Joanna Rogalska; Małgorzata Gałażyn-Sidorczuk; Alicja Roszczenko; Nazar M Smereczański
Journal:  Nutrients       Date:  2021-01-31       Impact factor: 5.717
  5 in total

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