Literature DB >> 12872620

[The effect of cerebrolysin on cognitive functions in childhood autism and in Asperger syndrome].

M G Krasnoperova, V M Bashina, I A Skvortsov, N V Simashkova.   

Abstract

Nineteen children with childhood autism and 8 with Asperger's syndrome aged 2-8 year, were treated with cerebrolysin (CL) in inpatient clinic. All the patients received 10 microinjections (intramuscularly and perinervously) of 0.1 ml CL daily during 5 days. Clinical study was combined with device estimation of cognitive functions and communicative skills. CL therapy resulted in improvement of cognitive functions (expressive and receptive speech, fine motoring, playing). Positive effects were revealed in all the patients with Asperger's syndrome and in 89% of the patients with childhood autism. Any negative effects were not found. With regard to cognitive functions development, therapeutic efficacy proved to be more pronounced in the patients with Asperger's syndrome as compared to childhood autistic group (p < 0.005).

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Year:  2003        PMID: 12872620

Source DB:  PubMed          Journal:  Zh Nevrol Psikhiatr Im S S Korsakova        ISSN: 1997-7298


  2 in total

1.  Cerebrolysin effects on neurological outcomes and cerebral blood flow in acute ischemic stroke.

Authors:  Mohammad Reza Amiri-Nikpour; Surena Nazarbaghi; Babak Ahmadi-Salmasi; Tayebeh Mokari; Urya Tahamtan; Yousef Rezaei
Journal:  Neuropsychiatr Dis Treat       Date:  2014-12-03       Impact factor: 2.570

2.  Sera from children with autism induce autistic features which can be rescued with a CNTF small peptide mimetic in rats.

Authors:  Syed Faraz Kazim; Maria Del Carmen Cardenas-Aguayo; Mohammad Arif; Julie Blanchard; Fatima Fayyaz; Inge Grundke-Iqbal; Khalid Iqbal
Journal:  PLoS One       Date:  2015-03-13       Impact factor: 3.240

  2 in total

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