Literature DB >> 12871494

Fibrinogen gamma chain functions.

M W Mosesson1.   

Abstract

This review covers the functional features of the fibrinogen gamma chains including their participation in fibrin polymerization and cross-linking, their role in the initiation of fibrinolysis, their binding and regulation of factor XIII activity, their interactions with platelets and other cells, and their role in mediating thrombin binding to fibrin, a thrombin inhibitory function termed 'antithrombin I'.

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Year:  2003        PMID: 12871494     DOI: 10.1046/j.1538-7836.2003.00063.x

Source DB:  PubMed          Journal:  J Thromb Haemost        ISSN: 1538-7836            Impact factor:   5.824


  21 in total

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8.  Fibrinogen Hershey IV: a novel dysfibrinogen with a gammaV411I mutation in the integrin alpha(IIb)beta(3) binding site.

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Authors:  Mingzhang Guo; Dayle Daines; Jing Tang; Qiang Shen; Rachel M Perrin; Yoshikazu Takada; Sarah Y Yuan; Mack H Wu
Journal:  Arterioscler Thromb Vasc Biol       Date:  2009-01-02       Impact factor: 8.311

10.  Fibrinogen-elongated gamma chain inhibits thrombin-induced platelet response, hindering the interaction with different receptors.

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