Literature DB >> 12870921

JenPep: a novel computational information resource for immunobiology and vaccinology.

Helen McSparron1, Martin J Blythe, Christianna Zygouri, Irini A Doytchinova, Darren R Flower.   

Abstract

JenPep is a relational database containing a compendium of thermodynamic binding data for the interaction of peptides with a range of important immunological molecules: the major histocompatibility complex, TAP transporter, and T cell receptor. The database also includes annotated lists of B cell and T cell epitopes. Version 2.0 of the database is implemented in a bespoke postgreSQL database system and is fully searchable online via a perl/HTML interface (URL: http://www.jenner.ac.uk/JenPep).

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Year:  2003        PMID： 12870921     DOI： 10.1021/ci030461e

Source DB:  PubMed          Journal:  J Chem Inf Comput Sci        ISSN： 0095-2338


  20 in total

1.  Benchmarking B cell epitope prediction: underperformance of existing methods.

Authors:  Martin J Blythe; Darren R Flower
Journal:  Protein Sci       Date:  2004-12-02       Impact factor: 6.725

2.  Determinants of antigenicity and specificity in immune response for protein sequences.

Authors:  Yulong Wang; Wenjun Wu; Nicolas N Negre; Kevin P White; Cheng Li; Parantu K Shah
Journal:  BMC Bioinformatics       Date:  2011-06-21       Impact factor: 3.169

3.  An integrated approach to epitope analysis II: A system for proteomic-scale prediction of immunological characteristics.

Authors:  Robert D Bremel; E Jane Homan
Journal:  Immunome Res       Date:  2010-11-02

4.  Computer aided selection of candidate vaccine antigens.

Authors:  Darren R Flower; Isabel K Macdonald; Kamna Ramakrishnan; Matthew N Davies; Irini A Doytchinova
Journal:  Immunome Res       Date:  2010-11-03

5.  Viruses selectively mutate their CD8+ T-cell epitopes--a large-scale immunomic analysis.

Authors:  Tal Vider-Shalit; Ronit Sarid; Kobi Maman; Lea Tsaban; Ran Levi; Yoram Louzoun
Journal:  Bioinformatics       Date:  2009-06-15       Impact factor: 6.937

6.  Phase-dependent immune evasion of herpesviruses.

Authors:  Tal Vider-Shalit; Vered Fishbain; Shai Raffaeli; Yoram Louzoun
Journal:  J Virol       Date:  2007-07-03       Impact factor: 5.103

7.  Predicting peptide binding affinities to MHC molecules using a modified semi-empirical scoring function.

Authors:  Webber W P Liao; Jonathan W Arthur
Journal:  PLoS One       Date:  2011-09-22       Impact factor: 3.240

8.  Bcipep: a database of B-cell epitopes.

Authors:  Sudipto Saha; Manoj Bhasin; Gajendra P S Raghava
Journal:  BMC Genomics       Date:  2005-05-29       Impact factor: 3.969

9.  Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes.

Authors:  Valerie A Walshe; Channa K Hattotuwagama; Irini A Doytchinova; Mailee Wong; Isabel K Macdonald; Arend Mulder; Frans H J Claas; Pierre Pellegrino; Jo Turner; Ian Williams; Emma L Turnbull; Persephone Borrow; Darren R Flower
Journal:  PLoS One       Date:  2009-11-30       Impact factor: 3.240

10.  MHCBN 4.0: A database of MHC/TAP binding peptides and T-cell epitopes.

Authors:  Sneh Lata; Manoj Bhasin; Gajendra P S Raghava
Journal:  BMC Res Notes       Date:  2009-04-20
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