Literature DB >> 12870809

Takanawaenes, novel antifungal antibiotics produced by Streptomyces sp. K99-5278. I. Taxonomy, fermentation, isolation and biological properties.

Yong-Pil Kim1, Hiroshi Tomoda, Kousuke Iizima, Takashi Fukuda, Atsuko Matsumoto, Yoko Takahashi, Satoshi Omura.   

Abstract

Three new pentaene macrolides having a 28-membered ring, designated takanawaenes A, B and C, were isolated from the fermentation broth of Streptomyces sp. K99-5278 by solvent extraction, silica-gel column chromatography and HPLC. Takanawaenes showed antifungal activity against Aspergillus niger, Mucor racemosus, Candida albicans and Saccharomyces cerevisiae.

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Year:  2003        PMID: 12870809     DOI: 10.7164/antibiotics.56.448

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

1.  Genome Mining Revealed a High Biosynthetic Potential for Antifungal Streptomyces sp. S-2 Isolated from Black Soot.

Authors:  Piotr Siupka; Artur Piński; Dagmara Babicka; Zofia Piotrowska-Seget
Journal:  Int J Mol Sci       Date:  2020-04-07       Impact factor: 5.923

2.  CFTR Modulators Dampen Aspergillus-Induced Reactive Oxygen Species Production by Cystic Fibrosis Phagocytes.

Authors:  Alexander J Currie; Ellen T Main; Heather M Wilson; Darius Armstrong-James; Adilia Warris
Journal:  Front Cell Infect Microbiol       Date:  2020-07-24       Impact factor: 5.293

  2 in total

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