Literature DB >> 128708

Neuropathology of Huntington's chorea. Studies of the ventrobasal complex of the thalamus.

R Dom, M Malfroid, F Baro.   

Abstract

In seven cases of Huntington's chorea, the ventrolateral thalamus was studied by quantitative cytometry. A selective 50 percent atrophy of microneurons (internuncial cells) was found while the macroneurons did not show significant atrophy. Thalamic microneurons might be presynaptic and postsynaptic inhibitory cells. Their specific atrophy in Huntington's chorea thus could be related to the known decrease of gamma aminobutyric acid (GABA) in Huntington's chorea.

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Mesh：

Year:  1976        PMID： 128708     DOI： 10.1212/wnl.26.1.64

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  19 in total

1.  Basal ganglia alterations and brain atrophy in Huntington's disease depicted by transcranial real time sonography.

Authors:  T Postert; B Lack; W Kuhn; M Jergas; J Andrich; B Braun; H Przuntek; R Sprengelmeyer; M Agelink; T Büttner
Journal:  J Neurol Neurosurg Psychiatry       Date:  1999-10       Impact factor: 10.154

2.  Computed tomography for Huntington's disease.

Authors:  C F Terrence; J F Delaney; M C Alberts
Journal:  Neuroradiology       Date:  1977-06-27       Impact factor: 2.804

3.  Nerve cell loss in the thalamic centromedian-parafascicular complex in patients with Huntington's disease.

Authors:  H Heinsen; U Rüb; D Gangnus; G Jungkunz; M Bauer; G Ulmar; B Bethke; M Schüler; F Böcker; W Eisenmenger; M Götz; M Strik
Journal:  Acta Neuropathol       Date:  1996       Impact factor: 17.088

Review 4.  Huntington's disease: the coming of age.

Authors:  Mritunjay Pandey; Usha Rajamma
Journal:  J Genet       Date:  2018-07       Impact factor: 1.166

Review 5.  The current state of research with peripheral tissues in Huntington disease.

Authors:  G C Beverstock
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

Review 6.  How vital is sleep in Huntington's disease?

Authors:  Anna O G Goodman; Roger A Barker
Journal:  J Neurol       Date:  2010-03-24       Impact factor: 4.849

Review 7.  Genetics and neuropathology of Huntington's disease.

Authors:  Anton Reiner; Ioannis Dragatsis; Paula Dietrich
Journal:  Int Rev Neurobiol       Date:  2011       Impact factor: 3.230

8.  Huntington's disease (HD): degeneration of select nuclei, widespread occurrence of neuronal nuclear and axonal inclusions in the brainstem.

Authors:  Udo Rüb; Matthias Hentschel; Katharina Stratmann; Ewout Brunt; Helmut Heinsen; Kay Seidel; Mohamed Bouzrou; Georg Auburger; Henry Paulson; Jean-Paul Vonsattel; Herwig Lange; Horst-Werner Korf; Wilfred den Dunnen
Journal:  Brain Pathol       Date:  2014-03-03       Impact factor: 6.508

9.  The topographic distribution of brain atrophy in Huntington's disease and progressive supranuclear palsy.

Authors:  D M Mann; R Oliver; J S Snowden
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

10.  Loss of corticostriatal and thalamostriatal synaptic terminals precedes striatal projection neuron pathology in heterozygous Q140 Huntington's disease mice.

Authors:  Y P Deng; T Wong; C Bricker-Anthony; B Deng; A Reiner
Journal:  Neurobiol Dis       Date:  2013-08-19       Impact factor: 5.996
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