Literature DB >> 12870240

[Toxic pictures produced spiders bites in Chile: latrodectism and loxoscelism].

Hugo Schenone1.   

Abstract

Latrodectism, produced by the bite of Latrodectus spiders, is worldwide distributed, occurs in hot seasons, and affects mostly men when carrying out agricultural activities. The main symptoms are muscular pain and tremors, profuse perspiration, increased lacrimal, nasal and salival secretions, and hypertension. Symptoms last one week. Neostigmine is a very efficient drug in the treatment of this condition. Loxoscelism, caused by the bite of Loxosceles spiders, is worldwide distributed, affects individuals of all ages. It may present two clinical forms: cutaneous loxoscelism (CL) and viscerocutaneous loxoscelism (VCL). Both forms have been registered in all seasons, with a higher incidence in hot periods, and in bedrooms, when the person is sleeping or dressing. The cutaneous surface of limbs and face are most frequently affected. Local clinical manifestations are pain, edema and livedoid plaque, most of which evolve into a necrotic scar in CL, whereas hematuria, hemoglobinuria, jaundice, fever and sensorial involvement characterize VCL. If visceral involvement does not appear within 24 hours, it is probable that the diagnosis corresponds to CL, with a good prognosis. If a VCL patient survives 48 hours, the possibilities of recovery are high. The patients are successfully treated with parenteral antihistamines or corticosteroids in CL and corticosteroids in VCL.

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Year:  2003        PMID: 12870240

Source DB:  PubMed          Journal:  Rev Med Chil        ISSN: 0034-9887            Impact factor:   0.553


  8 in total

1.  Loxosceles gaucho venom-induced acute kidney injury--in vivo and in vitro studies.

Authors:  Rui V Lucato; Regina C R M Abdulkader; Katia C Barbaro; Glória E Mendes; Isac Castro; Maria A S F Baptista; Patrícia M Cury; Denise M C Malheiros; Nestor Schor; Luis Yu; Emmanuel A Burdmann
Journal:  PLoS Negl Trop Dis       Date:  2011-05-31

2.  First report of in vitro selection of RNA aptamers targeted to recombinant Loxosceles laeta spider toxins.

Authors:  Amalia Sapag; Catalina Salinas-Luypaert; Carlos Constenla-Muñoz
Journal:  Biol Res       Date:  2014-03-26       Impact factor: 5.612

3.  Phospholipase D from Loxosceles laeta Spider Venom Induces IL-6, IL-8, CXCL1/GRO-α, and CCL2/MCP-1 Production in Human Skin Fibroblasts and Stimulates Monocytes Migration.

Authors:  José M Rojas; Tomás Arán-Sekul; Emmanuel Cortés; Romina Jaldín; Kely Ordenes; Patricio R Orrego; Jorge González; Jorge E Araya; Alejandro Catalán
Journal:  Toxins (Basel)       Date:  2017-04-05       Impact factor: 4.546

4.  Nephrotic syndrome due to minimal change disease secondary to spider bite: clinico-pathological case of a non-described complication of latrodectism.

Authors:  Gonzalo P Méndez; Daniel Enos; José Luis Moreira; Fátima Alvaredo; David Oddó
Journal:  Clin Kidney J       Date:  2016-12-26

5.  Heterophilic antibodies in sera from individuals without loxoscelism cross-react with phospholipase D from the venom of Loxosceles and Sicarius spiders.

Authors:  Tomás Arán-Sekul; José M Rojas; Mario Subiabre; Victoria Cruz; William Cortés; Luis Osorio; Jorge González; Jorge E Araya; Alejandro Catalán
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2018-07-26

6.  Acanthocytosis and brain damage in area postrema and choroid plexus: Description of novel signs of Loxosceles apachea envenomation in rats.

Authors:  Luis Fernando Plenge-Tellechea; Ángel Daniel Hernández-Ramos; Juan Manuel Muñoz; Guillermo Barraza-Garza; Edna Rico-Escobar; David Meléndez-Martínez
Journal:  PLoS One       Date:  2019-02-07       Impact factor: 3.240

7.  Toxicological Characterization and Phospholipase D Activity of the Venom of the Spider Sicarius thomisoides.

Authors:  Tomás Arán-Sekul; Ivanka Perčić-Sarmiento; Verónica Valencia; Nelly Olivero; José M Rojas; Jorge E Araya; Andrés Taucare-Ríos; Alejandro Catalán
Journal:  Toxins (Basel)       Date:  2020-11-06       Impact factor: 4.546

8.  Brown Spiders' Phospholipases-D with Potential Therapeutic Applications: Functional Assessment of Mutant Isoforms.

Authors:  Thaís Pereira da Silva; Fernando Jacomini de Castro; Larissa Vuitika; Nayanne Louise Costacurta Polli; Bruno César Antunes; Marianna Bóia-Ferreira; João Carlos Minozzo; Ricardo Barros Mariutti; Fernando Hitomi Matsubara; Raghuvir Krishnaswamy Arni; Ana Carolina Martins Wille; Andrea Senff-Ribeiro; Luiza Helena Gremski; Silvio Sanches Veiga
Journal:  Biomedicines       Date:  2021-03-21
  8 in total

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