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Literature DB >> 12869616

Apical entry channels in calcium-transporting epithelia.

Ji-Bin Peng¹, Edward M Brown, Matthias A Hediger.

Abstract

The identification of the apical calcium channels CaT1 and ECaC revealed the key molecular mechanisms underlying apical calcium entry in calcium-transporting epithelia. These channels are regulated directly or indirectly by vitamin D and dietary calcium and undergo feedback control by intracellular calcium, suggesting their rate-limiting roles in transcellular calcium transport.

Entities: Chemical Gene

Mesh：

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Year: 2003 PMID： 12869616 DOI： 10.1152/nips.01440.2003

Source DB: PubMed Journal: News Physiol Sci ISSN： 0886-1714

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Cited

15 in total

1. Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels.

Authors: Kazuhiro Nakaya; Donald G Harbidge; Philine Wangemann; Bruce D Schultz; Eric D Green; Susan M Wall; Daniel C Marcus
Journal: Am J Physiol Renal Physiol Date: 2007-01-02

2. Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures.

Authors: Nicolás Montalbetti; Qiang Li; Yuliang Wu; Xing-Zhen Chen; Horacio F Cantiello
Journal: J Physiol Date: 2007-01-04 Impact factor: 5.182

Review 3. Mechanism of action of 1,25-dihydroxyvitamin D3 on intestinal calcium absorption.

Authors: Sylvia Christakos
Journal: Rev Endocr Metab Disord Date: 2012-03 Impact factor: 6.514

Review 4. TRPV5 and TRPV6 in Ca(2+) (re)absorption: regulating Ca(2+) entry at the gate.

Authors: Tom Nijenhuis; Joost G J Hoenderop; René J M Bindels
Journal: Pflugers Arch Date: 2005-07-26 Impact factor: 3.657

5. Vitamin D endocrine system and the intestine.

Authors: Sylvia Christakos; Liesbet Lieben; Ritsuko Masuyama; Geert Carmeliet
Journal: Bonekey Rep Date: 2014-02-05

Review 6. Recent advances in our understanding of 1,25-dihydroxyvitamin D(3) regulation of intestinal calcium absorption.

Authors: Sylvia Christakos
Journal: Arch Biochem Biophys Date: 2012-01-02 Impact factor: 4.013

Apical entry channels in calcium-transporting epithelia.

1. Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels.

2. Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures.

Review 3. Mechanism of action of 1,25-dihydroxyvitamin D3 on intestinal calcium absorption.

Review 4. TRPV5 and TRPV6 in Ca(2+) (re)absorption: regulating Ca(2+) entry at the gate.

5. Vitamin D endocrine system and the intestine.

Review 6. Recent advances in our understanding of 1,25-dihydroxyvitamin D(3) regulation of intestinal calcium absorption.

7. Transcellular calcium transport in mammary epithelial cells.

8. TRPV6 is not required for 1alpha,25-dihydroxyvitamin D3-induced intestinal calcium absorption in vivo.

9. Expression of epithelial calcium transport system in rat cochlea and vestibular labyrinth.

10. Identification of Nipsnap1 as a novel auxiliary protein inhibiting TRPV6 activity.