Literature DB >> 12869146

Childhood discoid lupus erythematosus: a Tunisian retrospective study of 16 cases.

Faïka Cherif1, Amel Mebazaa, Mourad Mokni, Dalenda El Euch, Mohamed Iadh Azaiz, Amel Ben Osman Dhahri.   

Abstract

Discoid lupus erythematosus (DLE) is uncommon in children. The clinical features of childhood DLE are similar to those of adult DLE in presentation and chronic course. However, children have a particularly high level of transition to systemic disease. We undertook a retrospective study of 16 children with DLE ranging in age from 2 to 15 years, seen over a 9-year period. Six were less than 10 years old at the onset of the disease. The sex ratio was equal. The frequency of childhood DLE was about 7% of the total number of DLE patients seen in our department. Photosensitivity was defined as a clinical history of induction or exacerbation of discoid lesions following sun exposure, and was present in 81% of patients. There was no progression to systemic lupus erythematosus (SLE); an average follow-up time was 10.5 months (2-30 months). We would like to emphasize the increased frequency of childhood DLE in our country and the importance of photosensitivity. However, follow-up data regarding transition to SLE is lacking, therefore we are unable to offer a prognosis to our patients.

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Year:  2003        PMID: 12869146     DOI: 10.1046/j.1525-1470.2003.20402.x

Source DB:  PubMed          Journal:  Pediatr Dermatol        ISSN: 0736-8046            Impact factor:   1.588


  4 in total

Review 1.  [Connective tissue diseases in childhood].

Authors:  K Gensch; S Gudowius; T Niehues; A Kuhn
Journal:  Hautarzt       Date:  2005-10       Impact factor: 0.751

Review 2.  A Systematic Review of the Progression of Cutaneous Lupus to Systemic Lupus Erythematosus.

Authors:  Paul Curtiss; Amanda M Walker; Benjamin F Chong
Journal:  Front Immunol       Date:  2022-03-11       Impact factor: 7.561

3.  Disease characteristics in patients with juvenile- and adult-onset systemic lupus erythematosus: A multi-center comparative study.

Authors:  Sherif M Gamal; Nermeen Fouad; Nora Yosry; Wael Badr; Nesreen Sobhy
Journal:  Arch Rheumatol       Date:  2021-12-24       Impact factor: 1.007

4.  Current treatment strategies: collagen vascular diseases in children.

Authors:  Aparna Palit; Arun C Inamadar
Journal:  Indian J Dermatol       Date:  2012-11       Impact factor: 1.494

  4 in total

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